A0A370TH56 · A0A370TH56_9HELO

Function

function

PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromatin
Cellular Componentnucleolus
Molecular Functionpeptidyl-prolyl cis-trans isomerase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    peptidylprolyl isomerase
  • EC number

Gene names

    • ORF names
      BP5553_07660

Organism names

  • Taxonomic identifier
  • Strain
    • BP 5553
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Pleuroascaceae > Venustampulla

Accessions

  • Primary accession
    A0A370TH56

Proteomes

Subcellular Location

Interaction

Subunit

Binds to histones H3 and H4.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region39-175Disordered
Compositional bias101-117Basic and acidic residues
Compositional bias125-139Basic and acidic residues
Compositional bias159-175Acidic residues
Region218-386Disordered
Compositional bias235-259Acidic residues
Compositional bias260-298Basic and acidic residues
Compositional bias315-358Basic and acidic residues
Domain412-498PPIase FKBP-type

Sequence similarities

Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    498
  • Mass (Da)
    53,718
  • Last updated
    2018-11-07 v1
  • Checksum
    F84A1D0CFBA04B64
MPLLPVALFGLEVPCGDVLVPATPDFPATFRITMAAIDPSEPAELEDTPNGTSRPRATLKLIRQVEDSDDEDDEDDEEAMRALLAQSSSDEDSESDEEANGGPSDPSKSKKARKQAALEQLIESLKGDASDEDMEDAPNGIVSKKANKKGKAKATSDDEESEDESDDGEDLDVEEFVLCTLDPEKNYQQPLDITVAENERVYFKVTGTHTIYLTGNYVIPDDDGHNHHHEVYDSDDDEDYDLSPDEDELDLEGDESDDLDDLPNPRVTEVDSEDEAPALVKKADKKGKNKRSADEIDAATSLDDIMAKSLKSQAAEEPKLSKKQLKKLKKNNGEAVAAKAEEPKSADPKDKSDKKVQFAKNLEQGPTGSEKPKAEAASAKDKGNKGALGVKNVGGVTIDDKKLGKGPACKKGNRVSMRYIGKLADGKVFDSNKSGKPFSFKLGAGEVIQGWDIGVAGMSVGGERRLIIPAKLAYGSRGQPGIPANSNLTFDVKLLEAK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias101-117Basic and acidic residues
Compositional bias125-139Basic and acidic residues
Compositional bias159-175Acidic residues
Compositional bias235-259Acidic residues
Compositional bias260-298Basic and acidic residues
Compositional bias315-358Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NPIC01000007
EMBL· GenBank· DDBJ
RDL34532.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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