A0A370PGP0 · A0A370PGP0_ASPPH

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site77-84GTP (UniProtKB | ChEBI)
Binding site141-145GTP (UniProtKB | ChEBI)
Binding site195-198GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial matrix
Cellular ComponentRNA polymerase III complex
Molecular FunctionDNA binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionribosome binding
Molecular FunctionRNA polymerase III activity
Biological Processpositive regulation of translation
Biological Processtranslation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit
  • EC number

Gene names

    • ORF names
      M752DRAFT_235593

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 13157
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus

Accessions

  • Primary accession
    A0A370PGP0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain68-248Tr-type G
Coiled coil880-907

Sequence similarities

Belongs to the GTP-binding elongation factor family. LepA subfamily.
Belongs to the RNA polymerase beta' chain family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,116
  • Mass (Da)
    236,551
  • Last updated
    2018-11-07 v1
  • Checksum
    1F3D7C747CD7B3BB
MRGCLQLARWLRAAPKCPAASLLKPPSGLANPARFFTTSTACWASRSRAPASQPSSDLESRIAAIPIDRYRNFCIVAHVDHGKSTLSDRLLELTGTIQPGMNKQVLDKLDVERERGITVKAQTCTMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFSQGLELIPVINKVDLPSADPERALDQMEQSFELDTESAVLVSAKTGLNVQQLLPTVVEKIPAPVGDVNNPLRMLLVDSWYDSYRGVICLVRVFDGEIRAGDQLVSFATGIKYFVGEVGIMYPNETAQSVLRAGQVGYIFFNPGMKRSKEAKIGDTYTKVGFEKVVEPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLCLNDRSITVQKESSHALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKLIWKDGKEEIISNPAKFPEDEELRGKISEIQEPYVVATLTLPDEYLGKVIELCESNRGVQKSLEYFTSTQVILKYELPLAQLVDDFFGKLKGSTKGYATLDYEESAWQTSNIVKLQLLVNKAPVDAVARLVHYSQVERLGRQWVTKFKEHVDRQLFEIVIQAAVGRKVVARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKKLRAVGNVSVSPCHDHHLTTAMQPPEGVQVDLGKAQVIDRVPKVIKELKFGVLSNDDIVSQGVVEVSDRKFFDLDHDRAVVANGPLDARMGISNKTSSCQTCGGTLQICNGHFGHVRLVLPAFHVGYFKRVITILQEVCKECSRILLPEADRRAYLREMRRPGLDNLRRGQIAKRINERCRKTRNCEACGAVNGVVKKAGTSALKITHDKFRAFNASTSVKKVPPPSKIVFDRSFDEARTSNAEVEKHYKKAQDDMNALRVLNLFKKISDTDCELLGLNPKEARPEMFLWQFIPAPPVCIRPSVGQDAASTEDDLTAKLGDIVQSNINLKNALLKGAPVQTIMECWDYMQLQIAVYINSDVPGLNKADLGKPIRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRVDEVAVPELVAKNMTYPEVVTRYNKEKLQQRVRNGTKKWPGANYIMKKGQTFKLFLKYGNLNMIADQLQEGDVIERHIEDGDIVLFNRQPSLHKLSILSHFAKVRPHRTFRLNECVCNPYNADFDGDEMNLHVPQTEEARAEAMELMGVKNNLATPKNGEPIISAIQDFISAAYILSSKDNFFDRRSFTQICLYMLGPQTRFDLPPPAVLKPQMLWTGKQVFNILMRPNKDDPVLVNLDAACRQFKAPKDGTPRDLDPKDSWLVIRNSEVMCGVMDKSTIGSGKKDNVFYIMLRDYGPVAAAEGMNRLSRLSARWFTNMGFSIGITDVYPSEKLLRSKHDLVETAYAQCDEVIAKYKAGTLEKYPGCDELQTMENQLSGILSKVRQQAGDECIAQLSKYNSPLIMATSGSKGSSINVSQMVALVGQQIIGGQRVQDGFQDRTLPHFPKNARQPPSKGFVRNSFFSGLEPTEFIFHAMSGREGLVDTAVKTAETGYMSRRLMKSLEDLSTRYDDTVRNSSAAIVQFQYGDDKLDPLDMEGKAKPVHFDRTFIHAESTTYKNDERSLLPAEIMEICEEMLSKERSKLVRKDLMGNELGYMDRSDHGVDQFESARDFLESIQQYVATKADKLISRGGDIDPNDERSQKGLNHTGKLTERTLRTFISSCLMKYKKAQVEAGHAVGAVGAQSIGEPGTQMTLKTFHFAGVAGMSITQGVPRIKEIINASKEISTPVVACELVTKDNIIAARIVKGRIEKTYLRDIIHYVRETWTGKEAYITVKINWKTIQDLALELKIENILSAIKNHKRFKADDLKFRCSRSHIHVYMDVDPSTKANLSKTEIAHTSADPFLRLKHLKRMLPDIQVLGHPQAFRAIIRTDETSTTNTLLVEGYGLRECMTTMGVDGLRTSTNNVMEMRDVLGIEAARTTIVQEISEVMKDMDIDPRHMQLLADVMTYKGEVLGITRFGLAKMRDSVLQLASFEKTADHLFDAGGAGRSDLIEGVSECIIMGKTVSLGTGAMEVVRKMNFFEGQIGARKTTFEDTWTEVYEAPLERAKAARRKRS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ851855
EMBL· GenBank· DDBJ
RDK41368.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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