A0A370NLY3 · A0A370NLY3_9BURK

  • Protein
    DNA translocase FtsK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

1777100200300400500600700
TypeIDPosition(s)Description
Binding site430-437ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionDNA binding
Biological Processcell division

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • DNA translocase FtsK

Gene names

    • ORF names
      DN412_30415

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S23
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Cupriavidus

Accessions

  • Primary accession
    A0A370NLY3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane28-48Helical
Transmembrane68-92Helical
Transmembrane119-142Helical
Transmembrane162-189Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain413-622FtsK

Sequence similarities

Belongs to the FtsK/SpoIIIE/SftA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    777
  • Mass (Da)
    84,439
  • Last updated
    2018-11-07 v1
  • Checksum
    453F9D8B59910D7C
MARATTTTRTDPSALPSRIGKLLGEVRWFLLLAVTLGFLCVLASYSKTDPGWSHANQVADIHNLGGRVGAWVADVLFFIFGFSAYWLAVLLVRRCWRGWRALTAELPERADHSLHRQGVTISWIGFGLTLFSSMGLEAIRMYPLRAALPRAPGGVLGDLLGGWLQVALGFTGATLLLLLLLAIGLSLFFHFSWLTVAEQIGGFVETLFLGFKARRESKQDRIIGEAAKVERKETVEVQRVRIEEATPVQIVRPQAVPKHERVEREKQQPLFADIQDSDLPPLSLLDPIPAHQETVSAETLEFTSRLIEKKLKDFGVEVKVVAAYPGPVITRYEIEPATGVKGSQVVNLARDLARSLSLVSIRVVETIPGKNYMGLELPNPKRQTVRLSEILGSQVYNESASSLTMALGKDIAGKPMVADLARMPHCMVAGTTGSGKSVGINAMILSLLYKAKAESVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGNALNWAVGEMERRYKLMSKLGVRNLAGYNKKIDEAAAREEKIPNPFSLTPDAPEPLDRLPTIVIVIDELADLMMVVGKKVEELIARIAQKARAAGLHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAETLLGMGDMLYLAPGTGLPVRVHGAFVSDEEVHRVVEKLKESGETNYIEGILEGGLTDDAGGGDGFGGGAGIGGGGEADPLYDQAVEVVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGMVSAMSGNGNRDILVQGGGAAREDD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QKWJ01000058
EMBL· GenBank· DDBJ
RDK06639.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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