A0A370NLY3 · A0A370NLY3_9BURK
- ProteinDNA translocase FtsK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids777 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 430-437 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | DNA binding | |
Biological Process | cell division |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Cupriavidus
Accessions
- Primary accessionA0A370NLY3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 28-48 | Helical | |||
Transmembrane | 68-92 | Helical | |||
Transmembrane | 119-142 | Helical | |||
Transmembrane | 162-189 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length777
- Mass (Da)84,439
- Last updated2018-11-07 v1
- Checksum453F9D8B59910D7C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QKWJ01000058 EMBL· GenBank· DDBJ | RDK06639.1 EMBL· GenBank· DDBJ | Genomic DNA |