A0A370NEZ7 · A0A370NEZ7_9BURK

  • Protein
    Phosphoenolpyruvate-protein phosphotransferase
  • Gene
    ptsP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site195Tele-phosphohistidine intermediate
Binding site302phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site339phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site442Mg2+ (UniProtKB | ChEBI)
Binding site465-466phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site466Mg2+ (UniProtKB | ChEBI)
Binding site476phosphoenolpyruvate (UniProtKB | ChEBI)
Active site513Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsP
    • ORF names
      DLM46_04235

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S27
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia

Accessions

  • Primary accession
    A0A370NEZ7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-129Phosphotransferase system enzyme I N-terminal
Domain161-231PEP-utilising enzyme mobile
Domain258-551PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    582
  • Mass (Da)
    64,006
  • Last updated
    2018-11-07 v1
  • Checksum
    9FF06F0CA11247D8
MSFTLHGIPVSRGIAIGRAYLIAPAALDVDHYLIEPTQIEGEVERFRSAQQLVHQELDALRADLAADAPSEMGAFINVHSMILNDAMLVQETIDLIRTRRYNVEWALTEQLERLSRHFDDIEDEYLRERKADIEQVVERVLKALAGASAALVDGVHGACDEMIVVAHDIAPADMMQFKTQTFQGFVTDLGGRTSHTAIVARSLGIPAAVGVQHASQLIRQDDLIIVDGDHGIVIVDPAPIVLEEYSYRQSEKALEQRKLQRLKFSPTQTLCGTRIELCANIELPDDARAAVDAGATGVGLFRTEFLFMNHKDRLPEEEEQFGAYRRAVELMNGLPVTIRTIDVGADKPLDSMGGGDGYETASNPALGLRAIRWSLSEPQMFLTQLRAILRASAFGKVKILIPMLAHAQEIDQTLDLIREAKRQLDDAGIAYDPNVQVGAMIEIPAAAIALPLFLKRLDFLSIGTNDLIQYTLAIDRADNSVAHLYDPLHPAVLHLIAFTLREAKRAGVPVSVCGEMAGDPALTRLLLGMGLTEFSMHPSQLLVVKQEILRSHLKTLEKPVADVLASFEPEEVQAALKRVALA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QHKS01000002
EMBL· GenBank· DDBJ
RDK04186.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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