A0A370N6Q2 · A0A370N6Q2_9BURK

Function

function

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.

Features

Showing features for binding site.

114820406080100120140
TypeIDPosition(s)Description
Binding site11Mg2+ 2 (UniProtKB | ChEBI)
Binding site11Mg2+ 1 (UniProtKB | ChEBI)
Binding site49Mg2+ 1 (UniProtKB | ChEBI)
Binding site71Mg2+ 1 (UniProtKB | ChEBI)
Binding site135Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmagnesium ion binding
Molecular Functionnucleic acid binding
Molecular FunctionRNA-DNA hybrid ribonuclease activity
Biological ProcessDNA replication, removal of RNA primer

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease H
  • EC number
  • Short names
    RNase H

Gene names

    • Name
      rnhA
    • ORF names
      DLM46_18375

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S27
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia

Accessions

  • Primary accession
    A0A370N6Q2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-143RNase H type-1

Sequence similarities

Belongs to the RNase H family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    148
  • Mass (Da)
    16,409
  • Last updated
    2018-11-07 v1
  • Checksum
    0D8B0A27F6A2EEC9
MTSDLIDIYTDGACKGNPGPGGWGALLRFGAQEKELFGGEANTTNNRMELMGVIAALEALKRPCKVVVHTDSQYVQKGISEWIHGWKKKGWMTAAKTPVKNADLWKRLDALVAQHEVEWRWVRGHSGHPENERADQLANRGVASLAEM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QHKS01000011
EMBL· GenBank· DDBJ
RDK01272.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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