A0A369M4D2 · A0A369M4D2_9ACTN
- ProteinAlkyl hydroperoxide reductase C
- GeneahpC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids187 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
Catalytic activity
- a hydroperoxide + NADH + H+ = an alcohol + NAD+ + H2O
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 47 | Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | NADH-dependent peroxiredoxin activity | |
Molecular Function | thioredoxin peroxidase activity | |
Biological Process | cell redox homeostasis | |
Biological Process | cellular response to stress | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkyl hydroperoxide reductase C
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Coriobacteriia > Eggerthellales > Eggerthellaceae > Gordonibacter
Accessions
- Primary accessionA0A369M4D2
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.
Structure
Sequence
- Sequence statusComplete
- Length187
- Mass (Da)20,955
- Last updated2018-11-07 v1
- MD5 ChecksumD25EC2001E6B9436D41F2294BBA7A6CB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PPTS01000002 EMBL· GenBank· DDBJ | RDB66292.1 EMBL· GenBank· DDBJ | Genomic DNA |