A0A369JGL2 · A0A369JGL2_HYPMA
- ProteinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- Genesdh1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids641 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Catalytic activity
- a quinone + succinate = fumarate + a quinol
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 332 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | electron transfer activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | succinate dehydrogenase (quinone) activity | |
Biological Process | mitochondrial electron transport, succinate to ubiquinone | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Tricholomatineae > Lyophyllaceae > Hypsizygus
Accessions
- Primary accessionA0A369JGL2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Peripheral membrane protein
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 91 | Tele-8alpha-FAD histidine | |||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 55-450 | FAD-dependent oxidoreductase 2 FAD binding | |||
Domain | 505-641 | Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal | |||
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length641
- Mass (Da)70,211
- Last updated2018-11-07 v1
- MD5 ChecksumC3085A71419520416F549DFE39C5D30C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LUEZ02000055 EMBL· GenBank· DDBJ | RDB21321.1 EMBL· GenBank· DDBJ | Genomic DNA |