A0A366R7Q6 · A0A366R7Q6_9HYPO

  • Protein
    Glutathione reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Maintains high levels of reduced glutathione in the cytosol.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site, active site.

146950100150200250300350400450
Type
IDPosition(s)Description
Binding site55FAD (UniProtKB | ChEBI)
Binding site184-191NAD+ (UniProtKB | ChEBI)
Binding site277NAD+ (UniProtKB | ChEBI)
Binding site318FAD (UniProtKB | ChEBI)
Active site458Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmitochondrion
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionglutathione-disulfide reductase (NADPH) activity
Molecular FunctionNADP binding
Biological Processcell redox homeostasis
Biological Processcellular response to oxidative stress
Biological Processglutathione metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione reductase
  • EC number

Gene names

    • ORF names
      FIESC28_08365

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FIESC_28
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium incarnatum-equiseti species complex

Accessions

  • Primary accession
    A0A366R7Q6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond46↔51Redox-active

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-333FAD/NAD(P)-binding
Domain356-467Pyridine nucleotide-disulphide oxidoreductase dimerisation

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    469
  • Mass (Da)
    50,852
  • Last updated
    2018-11-07 v1
  • Checksum
    D08C7015518B00CC
MAPVTKETDYLVIGGGSGGLASARMASSKFGVKATIVENKRLGGTCVNVGCVPKKVTYNAAALAEAIHDSKAYGFSVEETAPFDWSTFKTKRDAYIQRLNGIYERNLNNDKVDYVHGWARLTSKNQAEVTLDDQSKVLINAKKILVAVGGKPTIPPEIPGAEYGTNSDGFFDISTQPKKVAIVGAGYIAVEFAGMFNALGTETHLFIRHDTFLRNFDPMIQESVTKEYERLGVKLHKRSQASKVEKDSNGKLTVTYKDDQGNESVVSDVDNLIWAIGRTPETKGIGLEEAGVKLSEKGHIVVDEYQNTAVDNIYALGDVTGEVELTPVAIAAGRRLAHRLFGGPEYSTLKLDYNNVPSVVFSHPEVGSIGLTEPEAIEKYGKDNIKVYKTSFTAMYYAMMEPEQKGPTSYKLVVTGPEEKVVGLHIMGIGSGEMLQGFGVAIKMGATKADFDSCVAIHPTSAEELVTLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QKXC01000188
EMBL· GenBank· DDBJ
RBR13179.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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