A0A366QL72 · A0A366QL72_9HYPO
- Protein4-hydroxybenzoate polyprenyltransferase, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids348 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Catalytic activity
- 4-hydroxybenzoate + an all-trans-polyprenyl diphosphate = a 4-hydroxy-3-all-trans-polyprenylbenzoate + diphosphate
CHEBI:17879 + an all-trans-polyprenyl diphosphate RHEA-COMP:9564 = a 4-hydroxy-3-all-trans-polyprenylbenzoate RHEA-COMP:9514 + CHEBI:33019
Cofactor
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Secondary metabolite biosynthesis; terpenoid biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | 4-hydroxybenzoate decaprenyltransferase activity | |
Molecular Function | 4-hydroxybenzoate nonaprenyltransferase activity | |
Molecular Function | 4-hydroxybenzoate octaprenyltransferase activity | |
Biological Process | terpenoid biosynthetic process | |
Biological Process | ubiquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-hydroxybenzoate polyprenyltransferase, mitochondrial
- EC number
- Short names4-HB polyprenyltransferase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium incarnatum-equiseti species complex
Accessions
- Primary accessionA0A366QL72
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 54-72 | Helical | ||||
Sequence: YYLFFPCLFSTLMAAPMAM | ||||||
Transmembrane | 153-170 | Helical | ||||
Sequence: CLFYGVPSLILVASYPLA | ||||||
Transmembrane | 179-198 | Helical | ||||
Sequence: AVLGLTFSWGAIMGFPALGI | ||||||
Transmembrane | 204-224 | Helical | ||||
Sequence: TTALTAAACLYTSNIAWTVLY | ||||||
Transmembrane | 255-273 | Helical | ||||
Sequence: VLTGLAAAQISLLAVAGYA | ||||||
Transmembrane | 279-296 | Helical | ||||
Sequence: AFFIGSCGGAMVTLGLMI | ||||||
Transmembrane | 308-328 | Helical | ||||
Sequence: WWWFVNGCWITGGVVSLGLGA |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length348
- Mass (Da)37,290
- Last updated2018-11-07 v1
- Checksum00A43C2C5261F9AA