A0A365Q0K8 · A0A365Q0K8_9GAMM
- ProteinRenalase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids328 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidation of the 1,2-dihydro- and 1,6-dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers.
Catalytic activity
- 1,2-dihydro-beta-NAD + O2 + H+ = H2O2 + NAD+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 14 | FAD (UniProtKB | ChEBI) | |||
Binding site | 33-34 | FAD (UniProtKB | ChEBI) | |||
Binding site | 41 | FAD (UniProtKB | ChEBI) | |||
Binding site | 57-58 | FAD (UniProtKB | ChEBI) | |||
Binding site | 58-62 | substrate | |||
Binding site | 129 | FAD (UniProtKB | ChEBI) | |||
Binding site | 186 | substrate | |||
Binding site | 303 | FAD (UniProtKB | ChEBI) | |||
Binding site | 309 | substrate | |||
Binding site | 310 | FAD (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRenalase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Stutzerimonas
Accessions
- Primary accessionA0A365Q0K8
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length328
- Mass (Da)35,326
- Last updated2018-11-07 v1
- MD5 ChecksumFA36DCCE8657F9CE2C3AA82AD606D61A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QNTV01000001 EMBL· GenBank· DDBJ | RBA62686.1 EMBL· GenBank· DDBJ | Genomic DNA |