A0A365PSZ3 · A0A365PSZ3_9GAMM
- ProteinRibosomal RNA large subunit methyltransferase M
- GenerlmM
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids349 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
Catalytic activity
- cytidine2498 in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine2498 in 23S rRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 183 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 216-219 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 235 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 255 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 271 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 300 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | S-adenosylmethionine-dependent methyltransferase activity | |
Biological Process | methylation | |
Biological Process | rRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibosomal RNA large subunit methyltransferase M
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Stutzerimonas
Accessions
- Primary accessionA0A365PSZ3
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-70 | RlmM ferredoxin-like | |||
Domain | 82-157 | Ribosomal RNA large subunit methyltransferase M THUMP-like | |||
Domain | 181-273 | Ribosomal RNA methyltransferase FtsJ | |||
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length349
- Mass (Da)39,292
- Last updated2018-11-07 v1
- MD5 ChecksumB705B16121FF5FED107551B06EC7D461
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QNTV01000013 EMBL· GenBank· DDBJ | RBA55337.1 EMBL· GenBank· DDBJ | Genomic DNA |