A0A365PSM1 · A0A365PSM1_9GAMM

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site290-300substrate
Active site508Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processputrescine biosynthetic process from arginine
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      DQ403_14595

Organism names

  • Taxonomic identifier
  • Strain
    • SST2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Stutzerimonas

Accessions

  • Primary accession
    A0A365PSM1

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue110N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain102-350Orn/DAP/Arg decarboxylase 2 N-terminal
Domain376-458Arginine decarboxylase helical bundle
Domain586-635Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    637
  • Mass (Da)
    71,398
  • Last updated
    2018-11-07 v1
  • Checksum
    B1277FE8106C8ACA
MPVRRTRKDDGSQWTAADSRSVYGIRHWGAGYFSISDDGHVEVRPQGPNGAAVEFTGLIEQLRDAGLTLPLLVRFPDILQDRVRHLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIENIIATQNVSIGLEAGSKPELMAVLALAPKGGTIVCNGYKDREFIRLALMGQKLGHNVFIVIEKMSEVGMVIEEAAELKVIPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLTVIERFRAAGVEQGVRLLHFHMGSQIANLADYRDGFREAIRYYAELRALGLPVDHIDVGGGLGVDYDGTHSRNASSINYDIDEYAGTVVGMLKEFCDRQELPHPHIFSESGRAMTAHHAVLVMQVTDFERHNDEAPTIESYDELPEIVQALADLLGPTDPEMVTETYWRATHYMSEAAAQYASGKLSLAQKALAEQSYFAICRRLYNQLKARQRSHRAVLDELNDKLADKYICNFSVFQSLPDTWAIDQILPIVPLQRLSEEPVRRAVLQDLTCDSDGKIKHYVDEQSIENSMPVHEIQAGEEYFLGVFLVGAYQEILGDMHNLFGDTDSVNVYQREDGTFYHAGIETHDTIEDMLRYVHLSPEELMTYYRDKVSSARLSAKERTQYIDALRLGLTRSSYLTP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QNTV01000011
EMBL· GenBank· DDBJ
RBA56283.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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