A0A365PCK6 · A0A365PCK6_9ACTN

  • Protein
    Methionine--tRNA ligase
  • Gene
    metG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site144Zn2+ (UniProtKB | ChEBI)
Binding site147Zn2+ (UniProtKB | ChEBI)
Binding site157Zn2+ (UniProtKB | ChEBI)
Binding site160Zn2+ (UniProtKB | ChEBI)
Binding site351ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionmethionine-tRNA ligase activity
Biological Processmethionyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methionine--tRNA ligase
  • EC number
  • Alternative names
    • Methionyl-tRNA synthetase
      (MetRS
      )

Gene names

    • Name
      metG
    • ORF names
      DQ226_03815

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SST1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Dietziaceae > Dietzia

Accessions

  • Primary accession
    A0A365PCK6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain6-411Methionyl/Leucyl tRNA synthetase
Motif12-22'HIGH' region
Motif348-352'KMSKS' region
Domain422-527Methionyl-tRNA synthetase anticodon-binding

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    612
  • Mass (Da)
    67,257
  • Last updated
    2018-11-07 v1
  • Checksum
    01824561D5A12C70
MAKTVLTAVAWPYANGPRHIGHVSGFGVPSDVFSRYQRMAGNDVLMVSGTDEHGTPLLVQAEKEGVPVQELADRYNRVIVDDLAGLGLSYDLFTRTTTRNHYAVVQELFRGLHANGYMVAKTTTGAVSPSTGRTLPDRYIEGTCPICGDDGARGDQCDNCGNQLDPADLKNPVSKINGETPKFIETEHWFLDLPALADSLGDWLKGRKDWRPNVLKFSLNLLEDLRPRAMSRDIDWGIPIPVEGWQDRGDKKLYVWFDAVVGYLSASIEWAWRSGEPEAWRRWWTDPEAVSHYFMGKDNITFHSQIWPAELIGYDGRGAHGGEPGALGALNLPTEVVSSEFLTMSGSKFSSSRGVVIYVRDFLAEFGPDALRYFISVAGPENHDTDFTWDEYVRRTNSELVGGWGNLVNRTVSMAHKNFGEIPRPGTLSDLDAELLREAESAFATVGAHLERSRFKAGATEAMRIVGAANRYIAATEPWKLAKEPDQRERLGTVLHTALQVVSDANTLLTPYLPSAAQQIHGAIGGQGVWAAAPQVHEVTDDMPVELVGVGLPDAGRSYPVIMGDYAAEQARWARTEITPGTPLAKPSPLFAKVDPELAETGPSWAPIQQED

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QNTT01000006
EMBL· GenBank· DDBJ
RBA39133.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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