A0A365P5Y0 · A0A365P5Y0_9ACTN
- ProteinPyrroline-5-carboxylate reductase
- GeneproC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids307 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Catalytic activity
- L-proline + NAD+ = 1-pyrroline-5-carboxylate + NADH + 2 H+
Pathway
Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 67-70 | NADP+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | pyrroline-5-carboxylate reductase activity | |
Biological Process | L-proline biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyrroline-5-carboxylate reductase
- EC number
- Short namesP5C reductase ; P5CR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Dietziaceae > Dietzia
Accessions
- Primary accessionA0A365P5Y0
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-99 | Pyrroline-5-carboxylate reductase catalytic N-terminal | |||
Domain | 162-264 | Pyrroline-5-carboxylate reductase dimerisation | |||
Region | 267-307 | Disordered | |||
Sequence similarities
Belongs to the pyrroline-5-carboxylate reductase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length307
- Mass (Da)31,521
- Last updated2018-11-07 v1
- MD5 Checksum5EFAC41D9633546AF70F15305D510FEB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QNTT01000101 EMBL· GenBank· DDBJ | RBA30066.1 EMBL· GenBank· DDBJ | Genomic DNA |