A0A355QA38 · A0A355QA38_UNCDE
- ProteinPeptidoglycan glycosyltransferase RodA
- GenerodA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids370 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Peptidoglycan polymerase that is essential for cell wall elongation.
Catalytic activity
- [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H+
[GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate RHEA-COMP:9602 + CHEBI:60033 = [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate RHEA-COMP:9603 + CHEBI:58405 + CHEBI:15378
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell division site | |
Cellular Component | plasma membrane | |
Molecular Function | lipid-linked peptidoglycan transporter activity | |
Molecular Function | peptidoglycan glycosyltransferase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptidoglycan glycosyltransferase RodA
- EC number
- Short namesPGT
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Myxococcota > Myxococcia
Accessions
- Primary accessionA0A355QA38
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-32 | Helical | ||||
Sequence: WVLLSIVLMLCAVGIVAMYSA | ||||||
Transmembrane | 47-67 | Helical | ||||
Sequence: VIWMGLGLALALTATVIDYRI | ||||||
Transmembrane | 74-95 | Helical | ||||
Sequence: FLHLGAIFLLILVLFIGTGGPG | ||||||
Transmembrane | 162-178 | Helical | ||||
Sequence: GTALLLLIVFMPMIFLA | ||||||
Transmembrane | 183-203 | Helical | ||||
Sequence: WVLLASIVLGLCSLPIAWHFV | ||||||
Transmembrane | 273-293 | Helical | ||||
Sequence: WGFVGTLTVLLLFMALIFWSL | ||||||
Transmembrane | 305-327 | Helical | ||||
Sequence: AMLTVGVVTILTSHVLINIGMTI | ||||||
Transmembrane | 339-360 | Helical | ||||
Sequence: FFSYGGSAMLSQMFGIGLLLNV |
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the SEDS family. MrdB/RodA subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length370
- Mass (Da)40,824
- Last updated2018-11-07 v1
- Checksum05FAA63D20732EE2