A0A348ULB4 · A0A348ULB4_9GAMM
- ProteinAminopeptidase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids904 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 338 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 339 | Proton acceptor | |||
Binding site | 342 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 361 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Site | 423 | Transition state stabilizer | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | metalloaminopeptidase activity | |
Molecular Function | peptide binding | |
Molecular Function | zinc ion binding | |
Biological Process | peptide catabolic process | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminopeptidase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria
Accessions
- Primary accessionA0A348ULB4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5016715939 | 23-904 | Aminopeptidase | ||
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 44-225 | Aminopeptidase N-like N-terminal | |||
Domain | 268-485 | Peptidase M1 membrane alanine aminopeptidase | |||
Domain | 564-884 | ERAP1-like C-terminal | |||
Sequence similarities
Belongs to the peptidase M1 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length904
- Mass (Da)99,003
- Last updated2018-11-07 v1
- ChecksumBBB4655BD5A61136
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DMUF01000092 EMBL· GenBank· DDBJ | HAR30826.1 EMBL· GenBank· DDBJ | Genomic DNA |