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A0A343F035 · A0A343F035_9CRUS

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137450100150200250300350
TypeIDPosition(s)Description
Binding site80Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site94Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site179Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site193Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site198a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cytb

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Multicrustacea > Malacostraca > Eumalacostraca > Peracarida > Isopoda > Oniscidea > Crinocheta > Armadillidiidae > Armadillidium

Accessions

  • Primary accession
    A0A343F035

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane27-53Helical
Transmembrane74-95Helical
Transmembrane110-130Helical
Transmembrane142-163Helical
Transmembrane175-196Helical
Transmembrane217-242Helical
Transmembrane285-305Helical
Transmembrane317-336Helical
Transmembrane342-361Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-206Cytochrome b/b6 N-terminal region profile
Domain207-374Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    374
  • Mass (Da)
    42,419
  • Last updated
    2018-11-07 v1
  • MD5 Checksum
    A113DE2893D3C2998BD4E6E9AA009224
MRKNNPVLSIMNHALIDMPAPLNISSWWNFGSLLGICLLTQIITGLFLAMHFSGHVILAFDNLVYMCRDVNNGWLLRTLHANGASMFFICIYLHMGRSLYFNSFVMHNTWMIGVTILLLSMATAFLGYVLPWGQMSLWGASVITNLLSTIPYVGAALVQWLWGGFAVDTPTLTRFFSLHFILPFIILALVIIHILFLHQTGSNNPLGIKSNSLKSAFHPYFTMKDLLGMVIMVFLLFFLVLWDPNKLGDPENFNPANPLNSPPHIQPEWYYLFAYAILRSIPNKLGGVLALAASVMVFYTLPLLFSKQIQSSQFYPLNKCILWTFLSVVLLLTWIGAKPVEAPYIVTGQVLTLMYFSYFMLEPWLAKKWDLLTS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MF187611
EMBL· GenBank· DDBJ
ASN74411.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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