A0A343EHG1 · A0A343EHG1_9HEMI
- ProteinCytochrome b
- GeneCYTB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids378 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 84 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 98 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 183 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 197 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | |||
Binding site | 202 | a ubiquinone (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | mitochondrial electron transport, ubiquinol to cytochrome c |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Pentatomomorpha > Coreoidea > Coreidae > Coreinae > Anoplocnemis
Accessions
- Primary accessionA0A343EHG1
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 30-58 | Helical | |||
Transmembrane | 78-99 | Helical | |||
Transmembrane | 111-133 | Helical | |||
Transmembrane | 139-158 | Helical | |||
Transmembrane | 179-201 | Helical | |||
Transmembrane | 221-246 | Helical | |||
Transmembrane | 289-308 | Helical | |||
Transmembrane | 324-341 | Helical | |||
Transmembrane | 353-373 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-210 | Cytochrome b/b6 N-terminal region profile | |||
Domain | 211-378 | Cytochrome b/b6 C-terminal region profile | |||
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length378
- Mass (Da)42,893
- Last updated2018-11-07 v1
- ChecksumA9E5585A04CB7E03
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KY906099 EMBL· GenBank· DDBJ | ASH96381.1 EMBL· GenBank· DDBJ | Genomic DNA |