A0A343C0P1 · A0A343C0P1_CALNT

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strain
    • 3
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Sciuromorpha > Sciuridae > Callosciurinae > Callosciurini > Callosciurus

Accessions

  • Primary accession
    A0A343C0P1

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-43Helical
Transmembrane63-82Helical
Transmembrane94-110Helical
Transmembrane116-133Helical
Transmembrane145-167Helical
Transmembrane194-216Helical
Transmembrane228-251Helical
Transmembrane257-278Helical
Transmembrane285-303Helical
Transmembrane309-331Helical
Transmembrane343-361Helical
Transmembrane393-412Helical
Transmembrane437-456Helical

Keywords

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-109NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain112-402NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    459
  • Mass (Da)
    51,636
  • Last updated
    2018-11-07 v1
  • Checksum
    4AAA2660BA78D0E3
MLKIILPTILLAPLTWFSKNSMIWINPSIHSLMISLIALLTLIQPNDNDLVFSLTFFSDPLSSPLLVLTAWLLPLMIMASQNHLSNEPLTRKKLYILMLVSLQSFLIMTFSAMELIMFYVLFEATLIPTLIIITRWGNQAERLNAGLYFLFYTLVGSLPLLIALIYIQKSTGSLNFLISLYQTLNLPTTWTNNILWLACIMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGMIRISIFLHPVTSSMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAIMIQTPWSFMGATALMIAHGLTSSMLFCLANTNYERIHSRTMLLARGLQSILPLMGMWWLLASLTNLALPPTINLIGELFIILASFSWSNMTIILTGVNMLITALYSLYMLISTQRGKFTYHMSNISPSLTRENTLMFMHIFPLILLSMNPSIILGQPY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KY117542
EMBL· GenBank· DDBJ
ARH02790.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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