A0A341AIS9 · A0A341AIS9_NEOAA
- ProteinCyclin-dependent kinase inhibitor 3
- GeneCDKN3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids167 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
Catalytic activity
- O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 95 | Phosphocysteine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | perinuclear region of cytoplasm | |
Molecular Function | calmodulin-dependent protein phosphatase activity | |
Molecular Function | histone H2AXS140 phosphatase activity | |
Molecular Function | histone H2AXY142 phosphatase activity | |
Molecular Function | MAP kinase serine/threonine phosphatase activity | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | non-membrane spanning protein tyrosine phosphatase activity | |
Molecular Function | protein kinase inhibitor activity | |
Molecular Function | protein tyrosine phosphatase activity, metal-dependent | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity | |
Molecular Function | RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCyclin-dependent kinase inhibitor 3
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Whippomorpha > Cetacea > Odontoceti > Phocoenidae > Neophocaena
Accessions
- Primary accessionA0A341AIS9
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-12 | Polar residues | |||
Region | 1-21 | Disordered | |||
Domain | 75-142 | Tyrosine specific protein phosphatases | |||
Sequence similarities
Belongs to the protein-tyrosine phosphatase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length167
- Mass (Da)18,540
- Last updated2018-10-10 v1
- MD5 Checksum342AC0492BF30411C1D9BBFA4B52A026
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A341ALS0 | A0A341ALS0_NEOAA | CDKN3 | 212 | ||
A0A341AMY9 | A0A341AMY9_NEOAA | CDKN3 | 228 | ||
A0A341AKX6 | A0A341AKX6_NEOAA | CDKN3 | 183 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-12 | Polar residues | |||
Keywords
- Technical term