A0A341AB57 · A0A341AB57_NEOAA

Function

Catalytic activity

  • (R)-3-hydroxybutanoate(out) + 2 Na+(out) = (R)-3-hydroxybutanoate(in) + 2 Na+(in)
  • (S)-lactate(out) + 2 Na+(out) = (S)-lactate(in) + 2 Na+(in)
  • nicotinate(out) + 2 Na+(out) = nicotinate(in) + 2 Na+(in)
  • propanoate(out) + 2 Na+(out) = propanoate(in) + 2 Na+(in)
  • pyruvate(out) + 2 Na+(out) = pyruvate(in) + 2 Na+(in)
  • 4-methyl-2-oxopentanoate(out) + 2 Na+(out) = 4-methyl-2-oxopentanoate(in) + 2 Na+(in)
  • 5-oxo-L-proline(out) + 2 Na+(out) = 5-oxo-L-proline(in) + 2 Na+(in)
  • acetate(out) + 2 Na+(out) = acetate(in) + 2 Na+(in)
  • acetoacetate(out) + 2 Na+(out) = acetoacetate(in) + 2 Na+(in)
  • bromide(in) = bromide(out)
  • butanoate(out) + 2 Na+(out) = butanoate(in) + 2 Na+(in)
  • chloride(in) = chloride(out)
  • iodide(out) = iodide(in)
  • nitrate(in) = nitrate(out)

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentextracellular exosome
Molecular Functionorganic acid:sodium symporter activity
Biological Processpropanoate transmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Sodium-coupled monocarboxylate transporter 1
  • Alternative names
    • Electrogenic sodium monocarboxylate cotransporter
    • Solute carrier family 5 member 8

Gene names

    • Name
      SLC5A8

Organism names

Accessions

  • Primary accession
    A0A341AB57

Proteomes

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-34Helical
Transmembrane54-72Helical
Transmembrane84-108Helical
Transmembrane129-154Helical
Transmembrane160-178Helical
Transmembrane190-210Helical
Transmembrane240-259Helical
Transmembrane280-302Helical
Transmembrane340-363Helical
Transmembrane383-406Helical
Transmembrane412-433Helical
Transmembrane440-463Helical
Transmembrane521-541Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    611
  • Mass (Da)
    66,657
  • Last updated
    2018-10-10 v1
  • Checksum
    9467493EE6701AE4
MVSPRGIGTFVVWDYLVFAGMLLISAAVGIYYAFAGGGQQTSRDFLMGGRSMTAVPVAMSLTASFMSAVTVLGTPSEVYRFGAIFSIFAITYCFVVVLSAEVFLPVFYKLGITSTNEYLGLRFNKYVRLCGTILFIVQTILYTGIVIYAPALALNQVTGFNLWGAVVATGVVCTFYCTMGGLKAVIWTDVFQVGIMVAGFASLIIQAALIQGGIGTILNDAYHGARLNFWNFNPNPLQRHTFWTIVIGGTFTWTSIYGVNQSQVQRYISCKNRFQAKMSLYINLVALWLILTCTVLCGLALYSRYRDCDPWTAKKVSAPDQLMPYLALDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTLEDLVKSRFESLSERSLSWISQGMSVLFGALCIGMAALASLMGALLQAALSIFGMVGGPLLGLFALGILVPFANSIGALVGLLAGFTISLWVGIGAQLYPPLPERTMPLSLETYGCNSTYNGTDWMTTTEVPFSTSAFQVYNIERTPLMDNWYSLSYLYFSTVGTLVTIFVGMLISLSTGGRKQNIDPRFLLTKEDFLSNFDVFKKKKQVLDYKSHPIEDDGTDNPGFNHIELNCTDQSGRINGTRL

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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