A0A337SS16 · A0A337SS16_FELCA
- Proteinphosphopyruvate hydratase
- GeneENO1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids421 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O
Cofactor
Note: Mg2+ is required for catalysis and for stabilizing the dimer.
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 158 | substrate | |||
Binding site | 167 | substrate | |||
Active site | 210 | Proton donor | |||
Binding site | 245 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 293 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 293 | substrate | |||
Binding site | 318 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 318 | substrate | |||
Active site | 343 | Proton acceptor | |||
Binding site | 370-373 | substrate | |||
Binding site | 394 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | phosphopyruvate hydratase complex | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphopyruvate hydratase activity | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namephosphopyruvate hydratase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis
Accessions
- Primary accessionA0A337SS16
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-134 | Enolase N-terminal | |||
Domain | 142-421 | Enolase C-terminal TIM barrel | |||
Sequence similarities
Belongs to the enolase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length421
- Mass (Da)45,701
- Last updated2018-10-10 v1
- MD5 ChecksumE2D32486162DFFE06B88830BE83E160B
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2I2UTE6 | A0A2I2UTE6_FELCA | ENO1 | 522 | ||
M3W1X4 | M3W1X4_FELCA | ENO1 | 447 | ||
A0A5F5Y0W0 | A0A5F5Y0W0_FELCA | ENO1 | 522 | ||
M3WCP0 | M3WCP0_FELCA | ENO1 | 451 | ||
A0A337S0P1 | A0A337S0P1_FELCA | ENO1 | 463 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AANG04003082 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |