A0A337S859 · A0A337S859_FELCA

Function

Catalytic activity

Features

Showing features for site, binding site, active site.

152150100150200250300350400450500
Type
IDPosition(s)Description
Site297Important for autoinhibition of adenylyltransferase activity
Binding site379-382ATP (UniProtKB | ChEBI)
Active site426
Binding site430-437ATP (UniProtKB | ChEBI)
Binding site462-463ATP (UniProtKB | ChEBI)
Binding site470ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular FunctionAMPylase activity
Molecular FunctionATP binding
Molecular FunctionHsp70 protein binding
Molecular Functionprotein homodimerization activity
Biological Processprotein adenylylation
Biological Processregulation of IRE1-mediated unfolded protein response
Biological Processresponse to endoplasmic reticulum stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein adenylyltransferase FICD
  • EC number
  • Alternative names
    • AMPylator FICD
    • FIC domain-containing protein

Gene names

    • Name
      FICD

Organism names

  • Taxonomic identifier
  • Strain
    • Abyssinian
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis

Accessions

  • Primary accession
    A0A337S859

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane87-107Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for glycosylation.

TypeIDPosition(s)Description
Glycosylation338N-linked (GlcNAc...) asparagine

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, repeat, domain.

Type
IDPosition(s)Description
Region1-24Disordered
Repeat169-202TPR
Domain348-483Fido

Sequence similarities

Belongs to the fic family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    521
  • Mass (Da)
    58,259
  • Last updated
    2018-10-10 v1
  • Checksum
    8C63254DF905DF5F
MRNHPMARRGPGGGARRPAAEQGLGAGGCGASERLEVGCRVGSRARSCSEATEYVQGDCPSVQMTLMPMASVMAVTEPKWVSVWGRFLWVMLLSMVLGSLLALLLPLGPIEEQCLTMLKGFYLLRSKLDRVQHAVTKCTSPSTELSVTSGDAALLAVRTKASPAGKLEAKAALNQALEMKRQGKREKAHKLFLHALQMDPDFADALNEFGIFSEEDKDIVQADYLYARALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMSIPKGNSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSLEEQNEVIGMHAAMTYINTTLVSRIGSVAIGDVLEIHRRVLGYVDPVEAGRFRTTQVLVGHHIPPHPQDVEKQMEEFIQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTETTLDTLLFATTEYPVALPEAMPNHSGFKETLPVRP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AANG04002472
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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