A0A337S859 · A0A337S859_FELCA
- ProteinProtein adenylyltransferase FICD
- GeneFICD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids521 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-threonyl-[protein] + ATP = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate
Features
Showing features for site, binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 297 | Important for autoinhibition of adenylyltransferase activity | |||
Binding site | 379-382 | ATP (UniProtKB | ChEBI) | |||
Active site | 426 | ||||
Binding site | 430-437 | ATP (UniProtKB | ChEBI) | |||
Binding site | 462-463 | ATP (UniProtKB | ChEBI) | |||
Binding site | 470 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | AMPylase activity | |
Molecular Function | ATP binding | |
Molecular Function | Hsp70 protein binding | |
Molecular Function | protein homodimerization activity | |
Biological Process | protein adenylylation | |
Biological Process | regulation of IRE1-mediated unfolded protein response | |
Biological Process | response to endoplasmic reticulum stress |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein adenylyltransferase FICD
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Felis
Accessions
- Primary accessionA0A337S859
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 87-107 | Helical | |||
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, repeat, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-24 | Disordered | |||
Repeat | 169-202 | TPR | |||
Domain | 348-483 | Fido | |||
Sequence similarities
Belongs to the fic family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length521
- Mass (Da)58,259
- Last updated2018-10-10 v1
- Checksum8C63254DF905DF5F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AANG04002472 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |