A0A329X8Q6 · A0A329X8Q6_9GAMM

  • Protein
    Lipoprotein signal peptidase
  • Gene
    lspA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

116720406080100120140160
TypeIDPosition(s)Description
Active site123
Active site141

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      CKY02_08410
      , PH362_08445

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • LJ24-63
    • 09-20
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Photorhabdus

Accessions

  • Primary accession
    A0A329X8Q6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-30Helical
Transmembrane67-87Helical
Transmembrane99-117Helical
Transmembrane137-157Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    167
  • Mass (Da)
    18,802
  • Last updated
    2018-10-10 v1
  • Checksum
    1D08BF6E77FE2152
MNKPICSTGLRWLWLVVVVLILDLGSKQLVLQHFHLYESVPLIPYFNLTYAQNFGAAFSFLAEKDGWQRWFFAFIAVAISVVLMVMMYRASAKKKLSNIAYALIIGGALGNLFDRLVHGFVIDFIDFYVGDWHFPTFNIADMAICIGAGLVIIDSFLSPDEKTIKVG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAQMFO010000009
EMBL· GenBank· DDBJ
MDB6371981.1
EMBL· GenBank· DDBJ
Genomic DNA
NSCM01000008
EMBL· GenBank· DDBJ
RAX13227.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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