A0A328VTX6 · A0A328VTX6_9PSED

Function

function

Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site118acetyl-CoA (UniProtKB | ChEBI)
Binding site125-126acetyl-CoA (UniProtKB | ChEBI)
Binding site276acetyl-CoA (UniProtKB | ChEBI)
Binding site313acetyl-CoA (UniProtKB | ChEBI)
Active site340Proton acceptor
Binding site340glyoxylate (UniProtKB | ChEBI)
Binding site432Mg2+ (UniProtKB | ChEBI)
Binding site432glyoxylate (UniProtKB | ChEBI)
Binding site457-460glyoxylate (UniProtKB | ChEBI)
Binding site460Mg2+ (UniProtKB | ChEBI)
Binding site541acetyl-CoA (UniProtKB | ChEBI)
Active site631Proton donor

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmagnesium ion binding
Molecular Functionmalate synthase activity
Biological Processglyoxylate catabolic process
Biological Processglyoxylate cycle
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Malate synthase G
  • EC number

Gene names

    • Name
      glcB
    • ORF names
      DP092_21635

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MDMC224
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A328VTX6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue617Cysteine sulfenic acid (-SOH)

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-71Malate synthase N-terminal
Domain160-235Malate synthase G alpha-beta insertion
Domain337-577Malate synthase TIM barrel
Domain591-681Malate synthase C-terminal

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    725
  • Mass (Da)
    78,420
  • Last updated
    2018-10-10 v1
  • MD5 Checksum
    1FF918C5292DE0B81F4DE550EC4607B8
MTERVQVGGLQVAKALYDFVNNEAIPGTGIAADQFWAGAAAVIKDLAPKNHALLAKRDELQAQIDAWHQSRKGQAHDAAAYKAFLQEIGYLLPEPEDFHATTTNVDEEIARLAGPQLVVPVMNARFALNASNARWGSLYDALYGTDVISEEGGAEKGKGYNKVRGDKVIAFARAFLDEAAPLAAGSHVDSTGYAIVDGKLVVALKGGSNSGLRDDAQLVGFQGEASAPIAVLLKHNGLHFEIQIDASSPIGSTDAAGVKDVLMEAALTTIMDCEDSVAAVDADDKVVVYKNWLGLMKGDLAEEVSKGGKTFTRTMNPDRVYTKPDGSELTLHGRSLLFVRNVGHLMTNPAILDAAGNEIPEGIQDALFTSLIAVHNLIGNTSRKNTRTGSVYIVKPKMHGPEEVAFTSEIFARVEDVLGLARNTLKVGIMDEERRTTVNLKACIKAASERVVFINTGFLDRTGDEIHTSMEAGAVVRKAAMKSEAWIGAYENNNVDVGLATGLQGRAQIGKGMWAMPDLMAAMLEQKVAHPLSGANTAWVPSPTAAALHALHYHKVDVFARQAELAKRTPASVDDILTIPLAKDTNWSDEEIRNELDNNSQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQLLANWLRHGIVSEAQVVESLKRMAPVVDRQNANDPLYRPMAPDFDNNVAFQAALELVVEGTKQPNGYTEPVLHRRRREFKAKNGL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QLYU01000020
EMBL· GenBank· DDBJ
RAR31178.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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