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A0A326QSL8 · A0A326QSL8_9CYAN

  • Protein
    Adenine DNA glycosylase
  • Gene
    mutT
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Organism
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.
    EC:3.2.2.31 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Features

Showing features for binding site.

140250100150200250300350400
TypeIDPosition(s)Description
Binding site2778-oxo-dGTP (UniProtKB | ChEBI)
Binding site288-2918-oxo-dGTP (UniProtKB | ChEBI)
Binding site291Mg2+ (UniProtKB | ChEBI)
Binding site311Mg2+ (UniProtKB | ChEBI)
Binding site3738-oxo-dGTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
Molecular Function8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
Molecular Functionadenine/guanine mispair binding
Molecular Functionmetal ion binding
Molecular Functionoxidized purine DNA binding
Molecular Functionpurine-specific mismatch base pair DNA N-glycosylase activity
Biological Processbase-excision repair
Biological Processmismatch repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenine DNA glycosylase
  • EC number

Gene names

    • Name
      mutT
    • ORF names
      DCF18_03130

Organism names

  • Taxonomic identifier
  • Organism
    Cyanobium sp
  • Strain
    • ULC065bin1
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Cyanobium

Accessions

  • Primary accession
    A0A326QSL8

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain255-384Nudix hydrolase

Sequence similarities

Belongs to the Nth/MutY family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    402
  • Mass (Da)
    43,976
  • Last updated
    2018-10-10 v1
  • MD5 Checksum
    BF1161332E0232A9B36E14134FB3862B
MAGRRDAGWAERKEHLPLQQLRAALLAWGERHGRHSMPWKLRSDGRPPLDGEPLDPLRVWVAEVMLQQTQLAVALPYWQRWMSAFPDLPALAAADPQQVLLLWQGLGYYGRARRLQQGARQLLDASAPGADPWPRDLAGWLALSGVGRSTAGSILSSAFDQPFAILDGNAARVLARLIAAPRPPKRELAGFWRLSELLLDRQRPRAFNQALMDLGATVCTPRSPDCGRCPWRNSCAAYAAGDPARYPVKDAPRPLPFQVIGVGVVLDGRGRVLIDQRLPEGLLGGLWEFPGGKQEPGEAIAATIARELREELAIEAEVGEELITLEHSYSHKRLRFVVHLCRWLAGDPQPLASQQVRWVEPEGLAAFPFPAANARIIAALLERLAGAAPVAASGPTGECGEN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QBMM01000006
EMBL· GenBank· DDBJ
PZV24378.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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