A0A317QMV1 · A0A317QMV1_9ACTN

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site292Mg2+ (UniProtKB | ChEBI)
Binding site322Mg2+ (UniProtKB | ChEBI)
Binding site324Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • ORF names
      JD79_04121

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 45417
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Geodermatophilales > Geodermatophilaceae > Geodermatophilus

Accessions

  • Primary accession
    A0A317QMV1

Proteomes

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-56Disordered
Domain200-359Transketolase N-terminal
Domain540-772Pyruvate dehydrogenase E1 component middle

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    969
  • Mass (Da)
    107,666
  • Last updated
    2018-10-10 v1
  • Checksum
    99242273D4FA70B7
MPGHAQALVDDAPDGPFPPLAGRSGVTRAIPARDDGPMSAPQQGGDPTRDAGQPRAVITDGLPSQLVDTDPDETQEWVESLDSVVEHAGRGRARYLMLKLLQRSREQQVGVPALRSTDYINTIPPEREPYFPGDEETERRIRAYIRWNAAIMVHRAQRPGIGVGGHISSYASSASLYEVGFNHFFRGKDHPGGGDQIWFQGHASPGIYARAYLEGRLTEQQLDGFRQEVSHPGGGLSSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNRYLHSRGVKDTSDQHVWAFLGDGEMDEPESLGLIGLAAREELDNLTFVVNCNLQRLDGPVRGNGKVIQELESFFRGAGWNVIKVIWGREWDPLLAADRDGALVNLMNQTPDGDYQTYKAEDGAFVREHFFGRDPRTRKLVEGMSDKEVWDLSRGGHDYRKVYAAFKAAVEHKGQPTVILAKTIKGWTLGSHFEGRNSTHQMKKLTAEDLAAFRDRLYLPIPDEQLDKTLPPYYKPAPDSDEMQYMVERRRALGGAVPRRRSEFKTLKAPDDKALDVLRRGSGKQEVATTMAFVRLLKELLKDKELGPRFVPIIPDEARTFGMDSLFPSQKIYNPAGQRYTSVDRELMLAYKESEQGVILHEGINEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDSFWAAADQMTRGFVLGATAGRTTLNGEGLQHEDGHSLLLAQTNPAVVSYDPAFSYEVGHIVKDALARMYGEDPGAPLGGYRSPDVMYYLTVYNEPFQQPAEPEDLDVQGLLAGMYLYAPGSGEGHRAQVLASGVAVPWALRAQELLREDWGVSADVWSVTSWNELRRQADEVSEHNFLHPEEDPQVPYVTRRLQDAEGPVVAVSDWMRAVPDLIAPYVPGGMATLGTDGFGLSDTRPALRRHFHVDAESIVVRTLGALADRGQIDRSTVREAVERYRIRDVQAAPAEERTDPSPAT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QGTX01000001
EMBL· GenBank· DDBJ
PWW24928.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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