A0A317CKI1 · A0A317CKI1_9GAMM

  • Protein
    Thiol:disulfide interchange protein DsbD
  • Gene
    dsbD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionelectron transfer activity
Molecular Functionprotein-disulfide reductase (NAD(P)H) activity
Biological Processcell redox homeostasis
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Thiol:disulfide interchange protein DsbD
  • EC number
  • Alternative names
    • Protein-disulfide reductase
      (Disulfide reductase
      )

Gene names

    • Name
      dsbD
    • ORF names
      DKW60_06615

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JCM 18388
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Thiotrichales > Thiotrichaceae > Leucothrix

Accessions

  • Primary accession
    A0A317CKI1

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane376-407Helical
Transmembrane419-444Helical
Transmembrane456-476Helical
Transmembrane497-530Helical
Transmembrane536-561Helical
Transmembrane573-590Helical
Transmembrane596-616Helical
Transmembrane636-657Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_501647286623-803Thiol:disulfide interchange protein DsbD
Disulfide bond395↔517Redox-active
Disulfide bond716↔719Redox-active

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region327-355Disordered
Domain662-801Thioredoxin

Sequence similarities

Belongs to the thioredoxin family. DsbD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    803
  • Mass (Da)
    86,295
  • Last updated
    2018-10-10 v1
  • Checksum
    9EB98179D8288D35
MRNIMKAFFSVIVLLITTSLYAASDTLLRPSEAFKLTTETIDSQTVRATWTIEEGYYLYRDKIDFISETQDSSVANVFKPAGNPKKDPTFGEVDIYRGVVTFDISLQHNNSNSPQLIQLLSKSQGCADIGLCYPPQKQTVNVKLPPSFSNTATSETPLNNPISPVSLADELGISSITGTSEPDSITGIGGISSIGGNQANEPLPPDEAFRFDIIATDSNTLNARWNVTPGHYLYQHKIGFKVDGNKHNVTLGKPNLPEGKAYKDVYFGDVVTYDKDFEVTVPVSGYNETLEVITEYQGCSELTGICYPPQTKTELVDFSAFPPSTITKAQTGSDASNTTDATTTEKTATPTADTTTITESASQQSALSDALKNKGILAVIGLFFLGGLLLTFTPCVFPMIPILSGIITGQGEDLSRGKAFALSLAYVVPMALTYAAAGVIAGYTGANLQAALQNPWVLSMFALLFVILSLSMFGFYELQMPSAIQNKLNNISNTQRGGSLVGAGIMGVLSALIVGPCVTAPLIAALAYIADTKDVVLGGLSLFMLGMGMGAPLLVIGVSAGSVLPRAGAWMETVKHIFGVMMLGLAIWMLDRIVPPQITLLLSGILLVGSAIFLGATDSLNETSSGWKRLWKSSGLVSLLLGTILIIGAAAGSKSYFAPLSGLLATNSPNNSSDTLAEPTGLQFKKISSLSDLDSTLQLARNTNTPVMLDFYAYWCLPCREMEHTVFSDSDVVATLENTIVIQADVTDMNENDSALLKELEVFGPPHVIFYDRNGEERKDFRISGEMKLEPFKQHIQRFLSNV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QGKM01000013
EMBL· GenBank· DDBJ
PWQ99105.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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