A0A2Z6E110 · A0A2Z6E110_HYDTE

Function

function

Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionelectron transfer activity
Molecular Functionprotein-disulfide reductase (NAD(P)H) activity
Biological Processcell redox homeostasis
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Thiol:disulfide interchange protein DsbD
  • EC number
  • Alternative names
    • Protein-disulfide reductase
      (Disulfide reductase
      )

Gene names

    • Name
      dsbD
    • ORF names
      HPTL_2026

Organism names

Accessions

  • Primary accession
    A0A2Z6E110

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane239-267Helical
Transmembrane279-303Helical
Transmembrane315-337Helical
Transmembrane358-388Helical
Transmembrane394-417Helical
Transmembrane429-449Helical
Transmembrane455-476Helical
Transmembrane488-509Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_501647050324-656Thiol:disulfide interchange protein DsbD
Disulfide bond124↔130Redox-active
Disulfide bond254↔376Redox-active
Disulfide bond568↔571Redox-active

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain24-140Thiol:disulfide interchange protein DsbD N-terminal
Region158-215Disordered
Compositional bias163-207Polar residues
Domain243-444Cytochrome C biogenesis protein transmembrane

Sequence similarities

Belongs to the thioredoxin family. DsbD subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    656
  • Mass (Da)
    69,220
  • Last updated
    2018-10-10 v1
  • Checksum
    FD1B257BB163826F
MPRRLARGVLAALLFGALSFASAADPVPPEEAYPAEAYRLDAQTIAVEFTIRRDYYLYRDKIRVEPLTPGLQLGTPTIPPGKRKKDDFFGETEVFYDTLKVTVPVESAPATEAPWRIRVISQGCWNGGVCYPPLEQTLTVADAPPQRSWLGKLVGSVTAPDADAPRSSDSNPPSSTAAPSGTAPSMARASVPTGSATAATAPAPSSTSEPPLARAAAPLTDEAGSLAAFIAQQNRAAVLAAFFGFGLLLAFTPCVFPMIPILSGIIVGQGEAISRVRALGLTLTYVLAMAITYALAGVAAGLSGTMLQAALQHPAVLVTFALLFVALALSLFGFYELQLPPSWQTRLNQLAGSQQGGQLIGVAVMGVLSALIVGPCVAPPLVGALLYVSQTGDAVFGGVALFALGLGMGAPLIAVGVGARALLPKSGPWMNGVKAAMGVVMLALAWWLVRPVVADLWWLVGWAVLAVGTAVALGALEPLPIGARWPKRMGKALGLLLLAYGVAAFWGALAGNRDPLQPLAGFAGGNGGIPTANREALTFQPIRSVKELEARVANSTRPVLVDVRADWCISCIELERYTFTDPQVVALLRNVTLLKMDVTENSERDKAFLRHFQIFGPPALLFFAPGNPEELRQYRVTGFVDGPTFATHLRRWLGQT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias163-207Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP018558
EMBL· GenBank· DDBJ
BBD78280.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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