A0A2Z6E049 · A0A2Z6E049_HYDTE

Function

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide: step 2/2.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionphosphoribosylamine-glycine ligase activity
Molecular Functionphosphoribosylformylglycinamidine cyclo-ligase activity
Biological Process'de novo' IMP biosynthetic process
Biological Processadenine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoribosylformylglycinamidine cyclo-ligase
  • EC number
  • Alternative names
    • AIR synthase
    • AIRS
    • Phosphoribosyl-aminoimidazole synthetase

Gene names

    • Name
      purG
    • Synonyms
      purM
    • ORF names
      HPTL_1612

Organism names

Accessions

  • Primary accession
    A0A2Z6E049

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain56-161PurM-like N-terminal
Domain174-341PurM-like C-terminal

Sequence similarities

Belongs to the AIR synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    349
  • Mass (Da)
    36,713
  • Last updated
    2018-10-10 v1
  • Checksum
    A6D31A85FCB7BA4E
MAGLTYRDAGVDIDAGDALVDRIKPWAARTMRPEVLAGIGGFGALFALGQRYRDPVLVSGTDGVGTKLKLAFAWDRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGRLDVGVAERVVAGIAQACEACGCALIGGETAEMPDMYPDGEYDLAGFAVGVVERAQLLDGKNVAPGDVVLGLGSSGAHSNGYSLIRKILARSGLGEDPEADANVVLDGQPLRDAVMAPTRLYVKSILAARAAHRDAIKALAHITGGGLTENLPRVLPQGTAAEIERNGWPRPELFQWLQAHGEVADDEMLRVFNCGIGMTVVVDPGAADAVAATLAAMGERVYRIGAIVAHEGAPHVRYV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP018558
EMBL· GenBank· DDBJ
BBD77872.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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