A0A2Z6DX63 · A0A2Z6DX63_HYDTE

Function

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site62S-adenosyl-L-methionine 1 (UniProtKB | ChEBI)
Binding site68[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site72[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site74-76S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site75[4Fe-4S] cluster (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site119S-adenosyl-L-methionine 1 (UniProtKB | ChEBI)
Binding site120-121S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site152S-adenosyl-L-methionine 1 (UniProtKB | ChEBI)
Binding site179S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site191S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site216S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site250S-adenosyl-L-methionine 2 (UniProtKB | ChEBI)
Binding site336S-adenosyl-L-methionine 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioncoproporphyrinogen dehydrogenase activity
Molecular Functioncoproporphyrinogen oxidase activity
Molecular Functionmetal ion binding
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Coproporphyrinogen-III oxidase
  • EC number

Gene names

    • Name
      hemN
    • ORF names
      HPTL_0637

Organism names

Accessions

  • Primary accession
    A0A2Z6DX63

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain53-287Radical SAM core

Sequence similarities

Belongs to the anaerobic coproporphyrinogen-III oxidase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    464
  • Mass (Da)
    52,585
  • Last updated
    2018-10-10 v1
  • Checksum
    3D1DDEFA4A4E80F9
MSQFSQAVVFDPELIRRFDIAGPRYTSYPTADRFVEAFGPEAYGEALASRAVAGVQRPLSLYVHIPYCNTICYYCACNKIITKDHSRSSRYLDYLEREMALVDEKLTGSRTVAQLHFGGGTPTFLHESEMRRLWAAIRRTFTLIEHGEYSIEVDPRKVGREQVFLLRELGFNRMSIGVQDFDPVVQRAVNRVQSLEETQGVLEAARAAGFHSVSFDLIYGLPHQSVARFAKTLDAVIALAPDRLSLYSYAHLPRLFMPQRRIDEATLPSAAEKLAILKMAIERLTDAGYVYIGMDHFAKPEDELAVAQREGRLHRNFQGYSTHAECDLVALGISAISKIGPYYAQNHKTEEPYYDALDRGELPTLRGVAMSPDDVLRRSIIQALMCHFELSIDAVEEANLIDFAHYFAPELADLREMEAAGLVTVSDRWITVLPKGRLLVRAIAMVFDRYLRADRERTRYSKVI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP018558
EMBL· GenBank· DDBJ
BBD76905.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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