A0A2Z6AUF7 · A0A2Z6AUF7_9BACT

  • Protein
    NADH-quinone oxidoreductase subunit B
  • Gene
    nuoB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

117420406080100120140160
TypeIDPosition(s)Description
Binding site46[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site47[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site112[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site144[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane respiratory chain complex I
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit B
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit B
    • NDH-1 subunit B

Gene names

    • Name
      nuoB
    • ORF names
      DFE_0138

Organism names

  • Taxonomic identifier
  • Strain
    • IS5
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Desulfovibrio

Accessions

  • Primary accession
    A0A2Z6AUF7

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-157NADH:ubiquinone oxidoreductase-like 20kDa subunit

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    174
  • Mass (Da)
    19,132
  • Last updated
    2018-10-10 v1
  • Checksum
    DE543E7FDEBF6C6F
MAAQDFSIREAVTTQDDPMVNLELVGKALDVCRAMSLWPMTFGLACCAIEMMSVGMARFDISRFGAEVFRPSPRQADLMIVAGTVSKKMAPAVVRLYEQMPAPKYVIAMGNCAISGGPFKFKGQYGIIEGVDQLIPVDVYVPGCPPRPEGLLEGLFKLQEKITGRRWWPEPDKG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP017378
EMBL· GenBank· DDBJ
BBD06864.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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