A0A2Z5UXW1 · A0A2Z5UXW1_9EUCA

  • Protein
    Cytochrome b
  • Gene
    Cyt b
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

138650100150200250300350
TypeIDPosition(s)Description
Binding site92Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site106Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site191Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site205Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site210a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      Cyt b

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Multicrustacea > Malacostraca > Eumalacostraca > Eucarida > Decapoda > Pleocyemata > Anomura > Paguroidea > Paguridae > Pagurus

Accessions

  • Primary accession
    A0A2Z5UXW1

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane39-66Helical
Transmembrane86-107Helical
Transmembrane119-142Helical
Transmembrane148-175Helical
Transmembrane187-208Helical
Transmembrane238-259Helical
Transmembrane297-317Helical
Transmembrane329-349Helical
Transmembrane356-381Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-218Cytochrome b/b6 N-terminal region profile
Domain219-386Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    386
  • Mass (Da)
    44,069
  • Last updated
    2018-10-10 v1
  • Checksum
    20612F1CAE2396D9
MKMPVRKTMKMPVRKTHPLIKIINGALVDMPLPSNISTFWNFGSLLGLCLVIQILTGLFLSMHYTAHVDLAFSSVAHIHRDVNYGWLIRSMHANGASFFFVCLYLHIGRGIYYGSYVNIPAWMIGVIILFLVMATAFLGYVLPWGQMSFWGATVITNLFSAIPYVGTYLVNWIWGGFAVENATLTRFYSLHFLFPFVVAALSAVHIVFLHQLGAGNPLGISSQVDKVPFHPYFTYKDIVGFVVMLWALLILSLLFPFALMDPDNFIPANPMVTPKHIQPEWYFLFAYAILRSIPNKALGVIALVLSVAALMTFPFTHKSKFKGLTFYPINQWLFWFFISMVIQLTWIGARPVEEPYILTGQILTFLYFSFYIVNPLVLRWWDTKMN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LC222524
EMBL· GenBank· DDBJ
BBB16177.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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