A0A2Z5E3V3 · A0A2Z5E3V3_9NEOB

  • Protein
    Pro-opiomelanocortin
  • Gene
    POMC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Stimulates the adrenal glands to release cortisol.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Cellular Componentsecretory granule
Molecular FunctionG protein-coupled receptor binding
Molecular Functionhormone activity
Biological Processregulation of corticosterone secretion

Keywords

  • Molecular function

Names & Taxonomy

Protein names

  • Submitted names
    • Pro-opiomelanocortin

Gene names

    • Name
      POMC

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Neobatrachia > Ranoidea > Boophinae > Boophis

Accessions

  • Primary accession
    A0A2Z5E3V3

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-24Polar residues
Region1-25Disordered
Region38-70Disordered
Compositional bias50-70Basic and acidic residues
Domain63-101Pro-opiomelanocortin/corticotropin ACTH central region
Region143-164Disordered

Sequence similarities

Belongs to the POMC family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    164
  • Mass (Da)
    19,279
  • Last updated
    2018-10-10 v1
  • Checksum
    F81C8101E5AAD8FF
RWNKFGRRNSTSSDNNNNNNGGYKREDIANYPILNLFQGSDNQNAQDGNLEEESVDRQDSKRSYSMEHFRWGKPVGKKRRPIKVFPTDAEEESSESFPLELRRELSLEFDYPDTNSEEDLDEGELLDGPVKKDRKYKMHHFRWEGPPKDKRYGGFMTPERSQTP

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias1-24Polar residues
Compositional bias50-70Basic and acidic residues
Non-terminal residue164

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH422826
EMBL· GenBank· DDBJ
AXB74387.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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