A0A2Z4LZ57 · A0A2Z4LZ57_SPAAU

Function

Catalytic activity

  • (9Z)-octadecenoate + 1,2-di-(9Z-octadecenoyl)-glycerol + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1,3-di-(9Z-octadecenoyl)-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 2,3-di-(9Z)-octadecenoyl-sn-glycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • (9Z)-octadecenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.20 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.76 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecan-1-ol + hexadecanoyl-CoA = CoA + hexadecanyl hexadecanoate
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; glycerolipid metabolism.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site454

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functiondiacylglycerol O-acyltransferase activity
Molecular Functionretinol O-fatty-acyltransferase activity
Biological Processtriglyceride biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acyltransferase

Gene names

    • Name
      LOC115578741

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Spariformes > Sparidae > Sparus

Accessions

  • Primary accession
    A0A2Z4LZ57

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane118-139Helical
Transmembrane159-180Helical
Transmembrane192-216Helical
Transmembrane222-239Helical
Transmembrane321-340Helical
Transmembrane362-381Helical
Transmembrane436-453Helical
Transmembrane465-483Helical
Transmembrane495-513Helical

Keywords

Interaction

Subunit

Homodimer or homotetramer; both forms have similar enzymatic activities.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-87Disordered
Compositional bias43-65Basic and acidic residues
Compositional bias66-86Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    524
  • Mass (Da)
    60,244
  • Last updated
    2018-10-10 v1
  • Checksum
    B5E8B8668A88E1DC
MSDRAEMRGPVTRRRRTTISGGGNGAIGVKQASGSKSHEAGEKPPLCPAKAKKDEVDRHASNNGKVDKQMRVSGEQQLANTPRKQRSAVEDINDRLSCHVLQESLLSSASGYSNYRGILNWCVVMLVLSNARLFLENIIKYGILVDPIQVVSLFLKDPYSWPAACLIIVSNVFILAALYTERRLAVGTISEMTGLILHMFNLTSLLIFPSATVLSVPSMTPVGGVLSLGVYTVLFLKLYSYQDTNRWCREIRQAKAKRLTRSYSCPSVAQSNGSAVHAHVTYPGNLTHRDMYYFVFAPTLCYQLNFPRSSRIRKRFLMRRLFEMLFFTQLLVGLIQQWMVPTIQNSMKPFQEMDFSRMMERLLKLAVPNHLIWLIFFYWFFHSSMNFVAELLQFGDREFYKDWWNSETVTYFWANWNIPVHKWCLRHFYKPMLRKGINKFCAQTAVFLVSAFFHEYLVSVPLKMFRLWAFMGMMAQVPLAWFVSRFLNGNYGNAAVWISLIIGQPVAVLMYVHDYYVIHYGGTT

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A671W6W7A0A671W6W7_SPAAULOC115578741440
A0A671W4Z0A0A671W4Z0_SPAAULOC115578741444
A0A671W3J6A0A671W3J6_SPAAULOC115578741496
A0A671W3L4A0A671W3L4_SPAAULOC115578741419

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias43-65Basic and acidic residues
Compositional bias66-86Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MG570176
EMBL· GenBank· DDBJ
AWX49624.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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