A0A2Z4HHV2 · A0A2Z4HHV2_9ABAC

Function

function

Nuclease that cleaves host 2',3'-cGAMP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site, site.

126320406080100120140160180200220240260
TypeIDPosition(s)Description
Active site64Proton donor
Site112Substrate binding
Active site208Proton acceptor; shared with catalytic histidine of dimeric partner
Site250Substrate binding
Site252Substrate binding

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Function2',3'-cyclic GMP-AMP binding
Molecular Functionnuclease activity

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • p26

Gene names

    • Name
      p26
    • ORF names
      HytaNPV_gp010

Organism names

Accessions

  • Primary accession
    A0A2Z4HHV2

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Domain

The substrate binding site is formed by the N-terminus of a monomer and the C-terminus of the opposite monomer.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    30,109
  • Last updated
    2018-10-10 v1
  • Checksum
    ED6F37788F569E60
MIKLLFLAIALMNTAATLSVYNVQYVVDENDKTMNITHVNGVRTTVRVIPPHGEILAREYDAMHQFPGVATDVMLTGTPSNRAILHVLLSDGVMLRTVADRVFTNFHVHRQRMIYGQLFTFATDDFSVAEKIYPGAPIFYNNKLVSVVTCRFDDYERGLVYFPVTGVRNDRLVSGQMHIDDRVVKVTRLQPGMSVYGRSQMPYSLGVKQLAMSAYNNRQMYRDWPRTAFVYHNERDIIISLVEGEFEISRVRFQGPLVEPQHK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH261376
EMBL· GenBank· DDBJ
AWW14370.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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