A0A2Z3XCX8 · A0A2Z3XCX8_9ENTR

Function

function

Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 manganese ions per subunit.

Pathway

Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (hydrolase route): step 1/1.

Features

Showing features for binding site.

131320406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site130Mn2+ 1 (UniProtKB | ChEBI)
Binding site155Mn2+ 2 (UniProtKB | ChEBI)
Binding site155Mn2+ 1 (UniProtKB | ChEBI)
Binding site157Mn2+ 1 (UniProtKB | ChEBI)
Binding site157Mn2+ 2 (UniProtKB | ChEBI)
Binding site159Mn2+ 1 (UniProtKB | ChEBI)
Binding site241Mn2+ 1 (UniProtKB | ChEBI)
Binding site241Mn2+ 2 (UniProtKB | ChEBI)
Binding site243Mn2+ 1 (UniProtKB | ChEBI)
Binding site243Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionagmatinase activity
Molecular Functionformimidoylglutamase activity
Molecular Functionmanganese ion binding
Biological ProcessL-histidine catabolic process to glutamate and formamide
Biological ProcessL-histidine catabolic process to glutamate and formate
Biological Processputrescine biosynthetic process from arginine, using agmatinase

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formimidoylglutamase
  • EC number
  • Alternative names
    • Formiminoglutamase
    • Formiminoglutamate hydrolase

Gene names

    • Name
      hutG
    • ORF names
      AN232_22490

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AR_0157
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Citrobacter

Accessions

  • Primary accession
    A0A2Z3XCX8

Proteomes

Family & Domains

Sequence similarities

Belongs to the arginase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    33,806
  • Last updated
    2018-10-10 v1
  • Checksum
    52D1029DF0B9D666
MTNWQPASPALWQGRDDRAESPTALRLFQTITLSPAFSPEMHSEQIALLGFACDEGVKRNQGRTGAAGAPDALRKALANLASHDGHQRLVDLGNIVAQAPDLEGAQQALRKAVQRCQQAKMRTLVLGGGHETAFAHGAGVLDAFPQAKVGIINLDAHLDLRHAEQATSGTPFRQLAHLCDEQQRGFHYACIGVSRAANTQALWDEAQRLGVTVVEDLHCDSAQAQLAQFASGADVIYLTIDLDVLPVWEMPAVSAPAALGVPLATLLGLIEPLCRSGKLQAVDMVEFNPRFDDDGRAARVAARLGWQIAHWWR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP029727
EMBL· GenBank· DDBJ
AWS97777.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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