A0A2X3G6F7 · A0A2X3G6F7_9LIST

Function

function

Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site5-8ATP (UniProtKB | ChEBI)
Binding site49substrate
Binding site120substrate
Binding site219-220ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaspartate kinase activity
Molecular FunctionATP binding
Biological Processhomoserine biosynthetic process
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processphosphorylation
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartokinase
  • EC number

Gene names

    • Name
      thrA
    • ORF names
      NCTC13940_00319

Organism names

Accessions

  • Primary accession
    A0A2X3G6F7

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain389-453ACT

Sequence similarities

Belongs to the aspartokinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    453
  • Mass (Da)
    49,982
  • Last updated
    2018-09-12 v1
  • MD5 Checksum
    3878F757BB9FDAFBBF4B54492E2963DE
MKVVKFGGSSLASGIQLMKVLDVVKNDDMRKIIVVSAPGKRFSDDTKVTDLLIDCAAKALLLEDTTEIFNKIISRYRDIVLDTGMDDSVISEISGNLTAILKSDKSNPDQFMDKMKASGEDNNAKLVAAFFNHQGITATYVNPKDAGLFVTEDHAGARVLPESYDNLFALRDYSGLVIFPGFFGYTKSGEISTFSRSGSDITGAIVANGVQAELYENFTDVDAVFVVNPAIVKKPQQVAELTYREMRELSYAGFSVFHDEALIPAFRAGIPVHIKNTNNPESTGTRVIRERDTSNGPVVGIASDDGFCSIYISKYLMNREIGFGRQVLEILERAGLNYEHMPSGIDDLTIILRENQLDATLEAKLIHELTHKLNADFVSIERSLSLIMIVGEAMRQNIGTTFRASRALSSANVNIEMINQGSSEVSIMFGVKKDDEHKAVQALYHEFFQEIEV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
UAWT01000001
EMBL· GenBank· DDBJ
SQC64122.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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