A0A2X0TKL6 · A0A2X0TKL6_ASF
- ProteinmRNA-capping enzyme
- GeneNP868R CDS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids868 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Probably catalyzes the second reaction in the mRNA cap formation pathway. Forms a covalent complex with GTP.
Catalytic activity
- a 5'-end diphospho-ribonucleoside in mRNA + GTP + H+ = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate
Pathway
mRNA processing; mRNA capping.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | virion component | |
Molecular Function | GTP binding | |
Molecular Function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity | |
Molecular Function | mRNA guanylyltransferase activity | |
Molecular Function | polynucleotide 5'-phosphatase activity | |
Molecular Function | RNA binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namemRNA-capping enzyme
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageViruses > Varidnaviria > Bamfordvirae > Nucleocytoviricota > Pokkesviricetes > Asfuvirales > Asfarviridae > Asfivirus
- Virus hosts
Accessions
- Primary accessionA0A2X0TKL6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Part of the viral DNA-directed RNA polymerase that consists of 8 polII-like subunits (RPB1, RPB2, RPB3, RPB5, RPB6, RPB7, RPB9, RPB10), a capping enzyme and a termination factor.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 594-868 | MRNA cap 0 methyltransferase | ||||
Sequence: GIYRAQTALISFIKQEIIQKISHQSWVIDLGIGKGQDLGRYLDAGIRHLVGIDKDQTALAELVYRKFSHATTRQHKHATNIYVLHQDLAEPAKEISEKVHQIYGFPKEGASSIVSNLFIHYLMKNTQQVENLAVLCHKLLQPGGMVWFTTMLGEQVLELLHENRIELNEVWEARENEVVKFAIKRLFKEDILQETGQEIGVLLPFSNGDFYNEYLVNTAFLIKIFKHHGFSLVQKQSFKDWIPEFQNFSKSLYKILTEADKTWTSLFGFICLRKN |
Sequence similarities
In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length868
- Mass (Da)99,902
- Last updated2018-09-12 v1
- Checksum7C596C531ECEDBB5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MG939583 EMBL· GenBank· DDBJ | AXZ95875.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MG939588 EMBL· GenBank· DDBJ | AXZ96158.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK128995 EMBL· GenBank· DDBJ | AYW34072.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MH910495 EMBL· GenBank· DDBJ | AZP53971.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MH910496 EMBL· GenBank· DDBJ | AZP54150.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR813622 EMBL· GenBank· DDBJ | CAD0059552.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FR682468 EMBL· GenBank· DDBJ | CAD2068463.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR899193 EMBL· GenBank· DDBJ | CAD7112612.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK333180 EMBL· GenBank· DDBJ | QBH90589.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK333181 EMBL· GenBank· DDBJ | QBH90774.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK645909 EMBL· GenBank· DDBJ | QDL88132.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK543947 EMBL· GenBank· DDBJ | QED90544.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK628478 EMBL· GenBank· DDBJ | QEY87907.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN172368 EMBL· GenBank· DDBJ | QGJ83463.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN715134 EMBL· GenBank· DDBJ | QGV56816.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MK940252 EMBL· GenBank· DDBJ | QIA61515.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN393476 EMBL· GenBank· DDBJ | QIE06890.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN393477 EMBL· GenBank· DDBJ | QIE07053.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT496893 EMBL· GenBank· DDBJ | QLF78629.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT847620 EMBL· GenBank· DDBJ | QOW02571.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT847621 EMBL· GenBank· DDBJ | QOW02758.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT847622 EMBL· GenBank· DDBJ | QOW02944.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT847623 EMBL· GenBank· DDBJ | QOW03130.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT166692 EMBL· GenBank· DDBJ | QOY24206.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT180393 EMBL· GenBank· DDBJ | QOY24407.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MT459800 EMBL· GenBank· DDBJ | QPB67627.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW465755 EMBL· GenBank· DDBJ | QSG73782.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW361944 EMBL· GenBank· DDBJ | QSH48660.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW656282 EMBL· GenBank· DDBJ | QST88185.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW396979 EMBL· GenBank· DDBJ | QTE18763.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW306190 EMBL· GenBank· DDBJ | QUQ60206.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW306191 EMBL· GenBank· DDBJ | QUQ60386.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW306192 EMBL· GenBank· DDBJ | QUQ60566.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LS478113 EMBL· GenBank· DDBJ | SPS73524.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR536725 EMBL· GenBank· DDBJ | VFV48035.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR722599 EMBL· GenBank· DDBJ | VVW94203.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LR722600 EMBL· GenBank· DDBJ | VVW94208.1 EMBL· GenBank· DDBJ | Genomic DNA |