A0A2W6XSY0 · A0A2W6XSY0_9FLAO

  • Protein
    Ketol-acid reductoisomerase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for binding site.

147450100150200250300350400450
TypeIDPosition(s)Description
Binding site217Mg2+ 2 (UniProtKB | ChEBI)
Binding site217Mg2+ 1 (UniProtKB | ChEBI)
Binding site221Mg2+ 1 (UniProtKB | ChEBI)
Binding site278substrate
Binding site389Mg2+ 2 (UniProtKB | ChEBI)
Binding site393Mg2+ 2 (UniProtKB | ChEBI)
Binding site414substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionisomerase activity
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase
  • EC number

Gene names

    • ORF names
      DI529_17130

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S2_003_000_R2_7
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Weeksellaceae > Chryseobacterium group > Chryseobacterium

Accessions

  • Primary accession
    A0A2W6XSY0

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-208KARI N-terminal Rossmann
Domain209-353KARI C-terminal knotted
Domain354-474KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    474
  • Mass (Da)
    52,286
  • Last updated
    2018-09-12 v1
  • Checksum
    A2FD01B033292CA4
MANYFNTLSLRDQLHQLGQAEFMDSSEFSDGVSALKGKKIVVVGCGAQGLNQGLNLRDSGLDVSYALRQEAIDQKRDSWKNATENNFKVGTYEELIPTADLVINLTPDKQHTSVINAVQPLMKQGATLSYSHGFNIVEEGMQIRKDLTVIMVAPKCPGSEVRAEYLRGFGVPTLIAVHPENDPQGKGWAEAKAYCVGTGGHKAGVLKSSFVAEVKSDLMGEQTILCGLLQTGSILSFDKMVEKGIDAGYASKLVQYGVEVITEALKHGGVSGMLDRLSNPAKLKAFELSEELKDIMRPLFQKHQDDIISGEFSKTMMEDWANGDANLLKWRAETGETAFEKTPAGDVKIEEQEYFDNYLLMSAFIRAGVELAFETMVEAGIKPESAYYESLHETPLIANTIARKKLFEMNRVISDTAEYGCYLFDQACKPLLADFMKSVDTDLVGKNFNEGKKTSVDNAQLVYVNDVLRNHPVE

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue474

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QFQW01000119
EMBL· GenBank· DDBJ
PZU79896.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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