A0A2W6XSY0 · A0A2W6XSY0_9FLAO
- ProteinKetol-acid reductoisomerase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids474 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Pathway
Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 217 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 217 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 221 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 278 | substrate | |||
Binding site | 389 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 393 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 414 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | isomerase activity | |
Molecular Function | ketol-acid reductoisomerase activity | |
Molecular Function | metal ion binding | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameKetol-acid reductoisomerase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Weeksellaceae > Chryseobacterium group > Chryseobacterium
Accessions
- Primary accessionA0A2W6XSY0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 19-208 | KARI N-terminal Rossmann | |||
Domain | 209-353 | KARI C-terminal knotted | |||
Domain | 354-474 | KARI C-terminal knotted | |||
Sequence similarities
Belongs to the ketol-acid reductoisomerase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length474
- Mass (Da)52,286
- Last updated2018-09-12 v1
- ChecksumA2FD01B033292CA4
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 474 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QFQW01000119 EMBL· GenBank· DDBJ | PZU79896.1 EMBL· GenBank· DDBJ | Genomic DNA |