A0A2W1B684 · A0A2W1B684_HELAM
- ProteinWee1-like protein kinase
- GeneHaOG213931
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids557 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-tyrosyl-[protein] = ADP + H+ + O-phospho-L-tyrosyl-[protein]
Cofactor
Note: Binds 2 magnesium ions per subunit.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | non-membrane spanning protein tyrosine kinase activity | |
Biological Process | mitotic cell cycle | |
Biological Process | negative regulation of G2/MI transition of meiotic cell cycle |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameWee1-like protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Noctuoidea > Noctuidae > Heliothinae > Helicoverpa
Accessions
- Primary accessionA0A2W1B684
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MPAVHHFLCVFILIESSTVVQT | ||||||
Chain | PRO_5015978419 | 23-557 | Wee1-like protein kinase | |||
Sequence: VTSSQLFVGHGSCRWFSNKISQLRRTYYSAGTFAWTQESNISRYNIEFIELGVIGRGEFGRVTRCVNKLDGCVYALKRSLRPVAGSAAERAALTEVYAHAALGKHPHVVRYYSAWAEDDHMIIQNEYCDGGSLQQKMENGPLSEPELLLLLAHIADGLAYIHSLQLVHMDVKPGNIFICSGEGQPSHDSDDGYDDEEVLYHHKYKIGDLGHVTCVSSPSVEEGDCRYLPKEVLQEDLTQLTKADIFAFGLTLFEAGGGGALPKNGQQWHDYRDGKLPELPNLSREYYSAWAEDDHMIIQNEYCDGGSLQQKMENGPLSEPELLLLLAHIADGLAYIHSLQLVHMDVKPGNIFICSGEGQPSHDSDDGYDDEEVLYHHKYKIGDLGHVTCVSSPSVEEGDCRYLPKEVLQEDLTQLTKADIFAFELPNLSREFNQLLRKMVDPDPSVRPSAARLRRHPLLHPAGNKTKTQLRRELAAAKMKNELLARKLQEAARELAAANMKNELLARKLQEAARELAAAKMKNELLARKLQEAAR |
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 70-481 | Protein kinase | ||||
Sequence: FIELGVIGRGEFGRVTRCVNKLDGCVYALKRSLRPVAGSAAERAALTEVYAHAALGKHPHVVRYYSAWAEDDHMIIQNEYCDGGSLQQKMENGPLSEPELLLLLAHIADGLAYIHSLQLVHMDVKPGNIFICSGEGQPSHDSDDGYDDEEVLYHHKYKIGDLGHVTCVSSPSVEEGDCRYLPKEVLQEDLTQLTKADIFAFGLTLFEAGGGGALPKNGQQWHDYRDGKLPELPNLSREYYSAWAEDDHMIIQNEYCDGGSLQQKMENGPLSEPELLLLLAHIADGLAYIHSLQLVHMDVKPGNIFICSGEGQPSHDSDDGYDDEEVLYHHKYKIGDLGHVTCVSSPSVEEGDCRYLPKEVLQEDLTQLTKADIFAFELPNLSREFNQLLRKMVDPDPSVRPSAARLRRHPLL | ||||||
Coiled coil | 489-551 | |||||
Sequence: KTQLRRELAAAKMKNELLARKLQEAARELAAANMKNELLARKLQEAARELAAAKMKNELLARK |
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length557
- Mass (Da)62,303
- Last updated2018-09-12 v1
- ChecksumE585D52B5781E755
Keywords
- Technical term