A0A2V8PNU1 · A0A2V8PNU1_UNCAI
- ProteinGlutathione hydrolase proenzyme
- Geneggt
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids615 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 424 | Nucleophile | |||
Binding site | 485-486 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 507 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione biosynthetic process | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase proenzyme
- EC number
- Cleaved into 2 chains
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Acidobacteriota
Accessions
- Primary accessionA0A2V8PNU1
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-28 | ||||
Chain | PRO_5016153121 | 29-615 | Glutathione hydrolase proenzyme | ||
Post-translational modification
Cleaved by autocatalysis into a large and a small subunit.
Keywords
- PTM
Interaction
Subunit
This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.
Structure
Sequence
- Sequence statusComplete
- Length615
- Mass (Da)66,915
- Last updated2018-09-12 v1
- MD5 ChecksumB2DA9767654D3F836544C501CE84FFD3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QHXE01000122 EMBL· GenBank· DDBJ | PYS64460.1 EMBL· GenBank· DDBJ | Genomic DNA |