A0A2V4U8D4 · A0A2V4U8D4_9GAMM

  • Protein
    Na(+)-translocating NADH-quinone reductase subunit F
  • Gene
    nqrF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site72[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site78[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site81[2Fe-2S] cluster (UniProtKB | ChEBI)
Binding site113[2Fe-2S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Functionelectron transfer activity
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Na(+)-translocating NADH-quinone reductase subunit F
  • EC number
  • Short names
    Na(+)-NQR subunit F
    ; Na(+)-translocating NQR subunit F
  • Alternative names
    • NQR complex subunit F
    • NQR-1 subunit F

Gene names

    • Name
      nqrF
    • ORF names
      DFP82_11714

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CECT 5889
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Psychrobacter

Accessions

  • Primary accession
    A0A2V4U8D4

Proteomes

Subcellular Location

Cell inner membrane
Cell membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical

Keywords

Interaction

Subunit

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain35-1292Fe-2S ferredoxin-type
Domain132-273FAD-binding FR-type

Sequence similarities

Belongs to the NqrF family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    411
  • Mass (Da)
    45,853
  • Last updated
    2018-09-12 v1
  • Checksum
    6E11C94D234E9B1F
MDYATAIGGVAMFTLIIMGLVAIILAARSRLVSSGDVTIHINDNSDNDVVTPAGGKLLQTLASEGIFLSSACGGGGTCAQCRCRVIEGGGSILPTEEGYFTQGEIRNHMRLACQVAVKQDMKIEIDPEFFDVQKWECEVVSNDNVATFIKELVLKIPEGEEVNFRAGGYVQLEAPPHEVHYKDFDVAEEYREDWDKFGIFNYVSKVDEPVIRAYSMANYPEEKGLIKFNIRIASPPPRGPDGIPPGKMSSWTFSLKPGDKVTVSGPYGEFFAKKTEAEMIFVGGGAGMAPMRSHIFDQLKRLNTDRKISFWYGARSIREMFYVEDYDQLQEDFSNFEWHVALSDPLPEDNWTGYTGFIHNVLLEEYLKGHPNPEDCEYYMCGPPMMNAAVIDMLHSMGVEDENIMLDDFGG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QJSU01000017
EMBL· GenBank· DDBJ
PYE36433.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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