A0A2V4GX96 · A0A2V4GX96_9PSED
- ProteinGlutathione hydrolase proenzyme
- Geneggt
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids596 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione biosynthetic process | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase proenzyme
- EC number
- Cleaved into 2 chains
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A2V4GX96
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MKFSTPLMSALCLLAGSGWACA | ||||||
Chain | PRO_5016118303 | 23-596 | Glutathione hydrolase proenzyme | |||
Sequence: DQVLPAPPELASGYRSGLQPVHASRHMVAAANPLASEAGRAMLRAGGSAIDAAIAMQMVLTLVEPQSSGIGGGGFILYWDGKRVQAFDGREAAPAGVSERLFLQADGSPMPFRAAQIGGRSVGVPGVLRALKLAHEQHGKLPWRDLFAPAIALARNGFAVSQRLHTLVEGDPFIARSPAMARYFLDDQGKPLAVGSILRNPALAHTLEQIAAQGPDAFYRGEIAEAIVAEVRSHANAGYLSLRDLQQYQARQREPVCGPYKAWQVCGMPPPSSGGVTVLQTLGMLEAVQRAAPQRDLAALRPLASASVARLEAPPMAVHLIAEAERLAYADRAQYLADSDYVPVPVNAMIDPAYLASRATRIGDYSMQRADPGRPHGANLALAADRSPLRISTSHLSAMDDRGQALAMTTSVEAAFGSHLMVKGFVLNNQLTDFSFIPEEHGMPVANRVQPGKRPLSAMAPTLVFSRASGELLASLGSPGGSQIIGYVNKALVGLLDWQLDPQQAAGLPNFGSRNAGTEVEAGLTSPALIRQLTTWGHEVTPMTMTSGMQIIQRSGKGWDGGADPRREGVALGD |
Post-translational modification
Cleaved by autocatalysis into a large and a small subunit.
Keywords
- PTM
Interaction
Subunit
This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 577-596 | Disordered | ||||
Sequence: SGKGWDGGADPRREGVALGD |
Sequence similarities
Belongs to the gamma-glutamyltransferase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length596
- Mass (Da)63,025
- Last updated2018-09-12 v1
- Checksum6CA7D80DFED6AF4C