A0A2V1B9G7 · A0A2V1B9G7_9HELO

  • Protein
    Catalase-peroxidase
  • Gene
    katG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Confers resistance to H2O2 in hyphae. May play an antioxidative role in fungal defense against the host-produced H2O2 (oxidative burst) at the early stage of plant infection.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site133Transition state stabilizer
Active site137Proton acceptor
Binding site310Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      DL98DRAFT_620753

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSE1049
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Helotiales incertae sedis > Cadophora

Accessions

  • Primary accession
    A0A2V1B9G7

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, cross-link.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_501579879219-780Catalase-peroxidase
Cross-link136↔269Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with Met-295)
Cross-link269↔295Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-136)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Keywords

Interaction

Subunit

Homodimer; disulfide-linked.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain170-452Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    780
  • Mass (Da)
    84,779
  • Last updated
    2018-09-12 v1
  • Checksum
    01DB0A2FB78E88C9
MAPSIRSLLIGFLPFVTGQGCPYASVDKRDLLVARGDEPSLTTLAHSFGKCPTLSDAAGAGTRSHDWWPCQLKLDVLRQFSPEQNPLGYTFDYTDAFSKLDYKALKSDVKALLKQSQPWWPADFGTYGGLFIRLSWHSAGTYRAVDGRGGGGMGQQRFAPLNSWPDNGNLDKARRLLWPIKKKYGKSISWADLMLLAGNAALEDMGFPVLGFGAGRPDTWQSDESVFWGAETTFVPKGNDIRYNGSTDFVGRANKLEEPLAATHMGLIYVNPQGPNGNGDPKMSALDIREAFGRMGMNDSETVALIAGGHAFGKAHGASSTALGPPPEAAPFEAQDFGWANSFGTGNADDAITSGLEVIWSKTPTKWSNDYLNSLFHNDWTLTKSPAGALQYIALKSTVDYPDPFNHTFRHATMLVSDLALREDPIYSAIAKPWVNDFPALTRAFAAAWFKLLHRDMGPIARYLGPEVPKQRFIWQDPLPAVTYNLINAADEDKLKAQILAAPGVTISNLVSVAWGSASTFRGGDKRGGANGARIALQPQASWAVNNPKQLKIVLSALNTIKTNFKKAHYDKQVSLADLIVLGGNAAIEKAAAAAGYNNIKVPFTKGRADAIQADTDIASFENLNPQGDGFRNYRNSSGWSLASTEELLVDKAQQLTLTAPEMTVLIGGLRALNANYDGSSHGILTANPGKLTNDFFTNLLDINTKWTPDSTGELFTGKDRSTNKQKWTATRADLVFSSHAELRAIAEVYAEAGGHDLLVTNFVAAWAKVMDLDRFDVKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ804384
EMBL· GenBank· DDBJ
PVH70092.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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