A0A2V0NUM7 · A0A2V0NUM7_9CHLO
- ProteinGlycoprotease 1
- GeneGCP1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids554 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Catalytic activity
- L-threonylcarbamoyladenylate + adenosine37 in tRNA = N6-L-threonylcarbamoyladenosine37 in tRNA + AMP + H+
Cofactor
Note: Binds 1 divalent metal cation per subunit.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | metal ion binding | |
Molecular Function | N(6)-L-threonylcarbamoyladenine synthase activity | |
Biological Process | tRNA threonylcarbamoyladenosine modification |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGlycoprotease 1
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorophyceae > CS clade > Sphaeropleales > Selenastraceae > Raphidocelis
Accessions
- Primary accessionA0A2V0NUM7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5016107733 | 22-554 | Glycoprotease 1 | ||
Interaction
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 27-53 | Disordered | |||
Domain | 79-178 | Gcp-like | |||
Domain | 200-337 | Gcp-like | |||
Compositional bias | 350-389 | Polar residues | |||
Region | 350-396 | Disordered | |||
Domain | 401-448 | Gcp-like | |||
Region | 508-528 | Disordered | |||
Region | 535-554 | Disordered | |||
Sequence similarities
Belongs to the KAE1 / TsaD family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length554
- Mass (Da)55,287
- Last updated2018-09-12 v1
- MD5 ChecksumC3D19733273A5212463A8E69129EB75C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 350-389 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BDRX01000021 EMBL· GenBank· DDBJ | GBF91039.1 EMBL· GenBank· DDBJ | Genomic DNA |