A0A2U9QV82 · A0A2U9QV82_RANTA

Function

function

VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Cellular Componentneuron projection
Molecular Functionneuropeptide hormone activity
Molecular Functionpeptide hormone receptor binding
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Processepinephrine secretion
Biological Processlearning or memory
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of potassium ion transport
Biological Processnegative regulation of smooth muscle cell proliferation
Biological Processphospholipase C-activating G protein-coupled receptor signaling pathway
Biological Processpositive regulation of endothelial cell proliferation
Biological Processpositive regulation of epinephrine secretion
Biological Processpositive regulation of penile erection
Biological Processpositive regulation of protein catabolic process
Biological Processregulation of protein localization

Keywords

  • Molecular function

Names & Taxonomy

Protein names

  • Submitted names
    • Vasoactive intestinal polypeptide

Gene names

    • Name
      Vip

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Cervidae > Odocoileinae > Rangifer

Accessions

  • Primary accession
    A0A2U9QV82

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_501613370326-170

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain81-103Glucagon / GIP / secretin / VIP family
Domain125-147Glucagon / GIP / secretin / VIP family

Sequence similarities

Belongs to the glucagon family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    170
  • Mass (Da)
    19,238
  • Last updated
    2018-09-12 v1
  • Checksum
    DBDFDEB321D3B2F1
METRSKRQLLVFLTLFSVLFSQTLAWPLFGAPSALRMGDRIPFEGANEPDQVSLKADTDILQEALAENDTPYYDVSRNVRHADGVFTSDYSRLLGQLSAKKYLESLIGKRVSNSISEDQGPIKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGESPDFLEELEK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MG924905
EMBL· GenBank· DDBJ
AWU58525.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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