A0A2U8ZWN4 · A0A2U8ZWN4_9ASTR
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids498 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast stroma | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > campanulids > Asterales > Asteraceae > Asteroideae > Senecioneae > Senecioninae > Dendrosenecio
Accessions
- Primary accessionA0A2U8ZWN4
Subcellular Location
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and two subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 45-68 | Disordered | ||||
Sequence: LGPIENASESKDPNRNDTEKNIRS | ||||||
Compositional bias | 54-68 | Basic and acidic residues | ||||
Sequence: SKDPNRNDTEKNIRS | ||||||
Domain | 234-498 | CoA carboxyltransferase N-terminal | ||||
Sequence: LWIQCESCYGLNYKKSFQSKMNLCEQCGYHLKMSSSDRIELLIDPGTWEPMDEDMVSLDPIQFHSEEEPYKKRIDSYQRKTGLTEAVQTGIGQLNGITVSIAVMDFQFMGGSMGSVVGEKITRLIEYATKEFLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQSNKKLFYVPILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPDGSQASEYLFQKGLFDLIVPRNPLKSVLSELFQLHTFFPLNQN | ||||||
Zinc finger | 238-260 | C4-type | ||||
Sequence: CESCYGLNYKKSFQSKMNLCEQC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length498
- Mass (Da)56,721
- Last updated2018-09-12 v1
- Checksum75FEA26763837B8B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 54-68 | Basic and acidic residues | ||||
Sequence: SKDPNRNDTEKNIRS |