A0A2U8QS91 · A0A2U8QS91_9FLAO

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site98Transition state stabilizer
Active site102Proton acceptor
Binding site270Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      DI487_01785

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MEBiC07310
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium

Accessions

  • Primary accession
    A0A2U8QS91

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link229↔255Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-31Disordered
Compositional bias11-25Polar residues
Domain135-414Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    739
  • Mass (Da)
    81,832
  • Last updated
    2018-09-12 v1
  • Checksum
    3B8AA82694DD1659
MEHSKNGNGKCPFTGAANSHSAGGGGTRNRDWWPNQLRLGILRQNSALSNPMGEEFEYAEAFKSLDLDAVKKDLNDLMTDSQEWWPADFGHYGPLFIRMAWHSAGTYRIGDGRGGAGAGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGKKISWADLMILAGNVALESMGFKTFGFAGGREDVWEPEEDIYWGSEQTWLAPSEAPKSRYSGERDLENPLAAVQMGLIYVNPEGPDGNPDPIAAAKDIRETFARMAMNDEETVALIAGGHTFGKTHGAGDPALVGAEPEAAGIEEQGLGWKSSFGSGKASDVITGGPEVTWTQTPTKWSNFFFENLFENEWELTKSPAGAYQWVAKATTESIPDAFDLTRRHRPTMLTTDLSLRLDPAYEKISRRFYENPDEFADAFARAWFKLTHRDMGPIARYLGPEVPKEDLIWQDPVPTVDHPLVDEKDIESLKNTILNSGLSIAELVSTAWASASTFRGSDKRGGANGARIRLAPQKYWAVNNPTQLSKVLDSLENIQKDFNNTQTNGKKISLADLIVLGGCAAIEKAAKEAGNVLKVPFTPGRTDATQEQTDVESFAVLEPIADGFRNYLKTKFVVSTEELLVDRAQLLTLTAPEMTVLIGGMRMLGTNHEGTQHGVFTKRQGTLTNDFFVNLLDMGTTWKAIDEHEEVFEGRDRSTNELKWTATRADLIFGSNSELRAIAEVYGSADAKQKFVHDFVAAWNKVMNLDRFDLK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias11-25Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP029463
EMBL· GenBank· DDBJ
AWM12724.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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