A0A2U8QP48 · A0A2U8QP48_9CAUD

Function

function

Baseplate central spike protein

Baseplate central spike complex-associated lysozyme that is essential for the localized hydrolysis of bacterial cell wall, so that the tail tube, through which the phage DNA is ejected, can penetrate to the host inner membrane. The tail lysozyme complex at the tip of the tail tube penetrates through the outer membrane into the periplasm. This way, lysozyme domain is released and locally digests the peptidoglycan layer to make a hole to let the tube penetrate to the inner membrane. Involved in the tail assembly.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
    EC:3.2.1.17 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

155950100150200250300350400450500550
TypeIDPosition(s)Description
Active site166Proton donor
Active site175Nucleophile

GO annotations

AspectTerm
Cellular Componentvirus tail, baseplate
Molecular Functionlysozyme activity
Biological Processcell wall macromolecule catabolic process
Biological Processdefense response to bacterium
Biological Processkilling of cells of another organism
Biological Processpeptidoglycan catabolic process
Biological Processsymbiont entry into host cell via disruption of host cell envelope
Biological Processsymbiont entry into host cell via disruption of host cell wall peptidoglycan
Biological Processviral tail assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Baseplate central spike protein
  • Alternative names
    • Peptidoglycan hydrolase
      (EC:3.2.1.17
      ) . EC:3.2.1.17 (UniProtKB | ENZYME | Rhea)

Gene names

    • ORF names
      vBEcoMNBG1_156

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Mosigvirus > Mosigvirus mar005p1

Accessions

  • Primary accession
    A0A2U8QP48

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50353493481-559Baseplate central spike protein

Expression

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-155Protein Gp5 N-terminal OB-fold

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    559
  • Mass (Da)
    61,449
  • Last updated
    2018-09-12 v1
  • Checksum
    48E763B6E9BCB045
MDPLKQGRVRVRVVGLHPAQRVQGDVQGIPTEKLPWMTVIQPITSASMSGIGGSVTGPVEGTRVYGHFLDKWKTNGIVLGTYGGIVREKPNRLEGFSDPTGQYPRRLGNDTNVLNQGGEAGYYSNSNVIQDNNLDYGINPDDTDLANIPEDDDPNFTITEMLRRDEGLRDKVYWDHLGYPTVGIGHLIVMEKTRDMSRINKLLSDQVGREVTGNPGTITLEEATALFEKDLAKMQKDIRSNSKVGPVYAKMNRSRQMALENMCFQMGVGGVAKFNTMLKAMATGDWKTAYKSGRDSLWFQQTKGRASRVTTIILTGNMESYGVPVKTPPSPGVGADLVTRNTDPEDPAGPPVPLDSRILFKEPESSYRGEYPYVHAMETESGHIQEFDDTPGNERYRLVHPTGSYEEVSPSGRRTRKTVEDLFDITNGDGNFLISGDKLVNVGANEIYYNMADRLHQIDGNDTIFIRGNQSKTVEGDGTLYVKGNIKIVVDGNADILVKGDAKTQVEGNHDYTVNGNVKWTVNGNVDMTVAGDWAETMSTMSSVASGQYTVDGSRIDIG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH243438
EMBL· GenBank· DDBJ
AWM11708.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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